Molecular Probes, Inc.

MOLECULAR PROBES, INC., 4849 PITCHFORD AVE
Eugene, OR 97402
114 Employees

SBIR Award Summary

Total Number of Awards 21
Total Value of Awards $310K
First Award Date 04/01/86
Most Recent Award Date 02/18/03

Key Personnel

Last Name Name Awards Contact
Haugland Richard Haugland 16
Brinkley John Brinkley 1
Agnew Brian J Agnew 1
Gee Kyle R Gee 2
Naleway John J Naleway 1

21 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-01-107
Budget: 02/18/03 - 01/31/04

DESCRIPTION (provided by applicant): Molecular Probes, Inc., has developed a fluorescence-based, Multiplexed Proteomics (MP) platform that allows for the simultaneous identification and characterization of glycosylation, phosphorylation and total protein in a single 2-D gel. With subpicomolar sensitivity, the system provides for the rapid qu...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/99 - 04/30/00

The use of caged compounds for the photolytic application of molecular bioeffectors into experimental systems with precise spatial and temporal control has proven very beneficial to several areas of the biosciences, including neuroscience, biochemistry, biophysics, etc. However, widespread implementation of the technology is presently limited by...

Phase 1 SBIR

Agency: National Aeronautics and Space Administration
Topic: 97-1
Budget: 01/01/97 - 12/31/97

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/95 - 09/30/96

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/95 - 09/30/96

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/94 - 05/31/95

We will prepare dyed latex particles that yield the optimal combinations of luminescence signal and other properties. These will include fluorescent particles that have enhanced Stokes shifts that are useful for simultaneous multi-color assays. The luminescence of the particles will usually be fluorescence; however, we also propose to develop ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/94 - 03/31/95

DESCRIPTION (Adapted from applicant's abstract): Continued development of novel fluorogenic enzyme substrates that yield intensely fluorescent precipitates near the site of enzymatic activity and their bioanalytical applications is proposed. Since the fluorescent precipitates represent pure dye, the substrates can be used to detect enzymatic ac...

Phase 1 SBIR

Agency: National Science Foundation
Topic: 1993
Budget: 01/01/93 - 12/31/93

USE OF THE ESCHERICHIA COLI BETA-GLUCURONIDASE GENE (GUS) AS A FUSION MARKER FOR ANALYSIS OF GENE EXPRESSION IN TRANSFORMED PLANTS HAS BEEN DEMONSTRATED. THE SYNTHESIS, BY CHEMICAL AND ENZYMATIC METHODS, OF A SERIES OF GLUCURONIC ACID CONJUGATES OF PLANT REGULATORY SUBSTANCES IS BEING DEVELOPED. RESEARCHERS ARE SYNTHESIZING CONJUGATES OF HERBICI...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/92 - 08/31/94

Molecular Probes plans to synthesize and characterize a large number of long wavelength diagnostic and photosensitizing dyes. The dyes are predominantly cationic and most examples are selected from the oxazine and thiazine classes of dyes. Several oxazine and thiazine derivatives were shown to be very potent and selectively toxic photosensitiz...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/92 - 02/28/93

This proposal involves development of novel fluorogenic substrates and their bioanalytical applications. Support is specifically requested for synthesis of fluorogenic enzyme substrates that yield intensely fluorescent precipitates near the site of enzymatic activity. Work in progress has demonstrated a significant potential for these reagents...

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