IA, Inc.

P.O. Box 1306
Ann Arbor, MI 48106
16 Employees

SBIR Award Summary

Total Number of Awards 40
Total Value of Awards $5.91MM
First Award Date 09/15/92
Most Recent Award Date 08/15/06

Key Personnel

Last Name Name Awards Contact
Downward James Downward 4 Message
Erb Judith L. Erb 24
Smith Mr. Richard Smith 11 Message
Shuler John L Shuler 1
Lysogorski Charles D. Lysogorski 1
Henderson Timothy M Henderson 1
Palmintera Palmintera 1
Downard James G. Downard 1 Message

40 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/15/06 - 05/14/08

DESCRIPTION (provided by applicant): While routine point-of-care blood chemistry measurements can now be performed in clinical settings, quantitative high-sensitivity immunoassay measurements cannot. Thus, low-level serum markers for a variety of life-threatening conditions, such as sepsis, cannot be performed at the point of care. IA Inc.'s imm...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/15/06 - 04/30/07

DESCRIPTION (provided by applicant): During Phase I work IA successfully applied evanescent sensing technology to the study of aryl hydrocarbon receptor (AhR)-mediated processes and provided discrimination between beneficial and harmful AhR ligands. When biosensors were used to assess the interaction of AhR with ligands, accessory proteins, and ...

Phase 1 SBIR

Agency: Environmental Protection Agency
Topic: 2006
Budget: 01/01/06 - 12/31/06

Perchlorate is a widely-used component of solid fuel, missile and rocket propellants, explosives and pyrotechnics. It has been shown to reduce iodide uptake into the thyroid gland. The EPA has found Perchlorate contamination in 18 states and believes contamination may exist in as many as 39 states. In early January 2005, the National Academy ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/05 - 04/30/06

DESCRIPTION (provided by applicant): During Phase I work IA successfully applied evanescent sensing technology to the study of aryl hydrocarbon receptor (AhR)-mediated processes and provided discrimination between beneficial and harmful AhR ligands. When biosensors were used to assess the interaction of AhR with ligands, accessory proteins, and ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/16/04 - 12/31/05

DESCRIPTION (provided by applicant): Biosensors provide rapid data containing information on molecular interactions that are not easily available using equilibrium assays or histochemical methods. This study will be the first of a series with long-term objectives of developing rapid biosensor methods applied to extracts of breast cancer biopsies...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/10/04 - 04/30/05

DESCRIPTION (provided by applicant): During Phase I work IA successfully applied evanescent sensing technology to the study of aryl hydrocarbon receptor (AhR)-mediated processes and provided discrimination between beneficial and harmful AhR ligands. When biosensors were used to assess the interaction of AhR with ligands, accessory proteins, and ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/03 - 08/31/05

DESCRIPTION (provided by applicant): The goal of this proposal is development of a multiplexed, portable real time evanescent fiber optic sensor instrument for quantifying the amount of specific DNA in a sample. During Phase I of this project, IA demonstrated the feasibility of monitoring DNA hybridization in real time using an evanescent fiber-...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/02 - 09/29/04

DESCRIPTION (provided by applicant): During Phase I, IA Inc. and HRL developed a novel, regenerable, fiber optic biosensor for monitoring in real-time, molecular interactions between estrogen receptor modulators and both hER-alpha and hER-beta. These biosensors don't require fluorophore labeling of receptor, are mor...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/06/02 - 08/31/03

DESCRIPTION (provided by applicant): The goal of this proposal is development of a multiplexed, portable real time evanescent fiber optic sensor instrument for quantifying the amount of specific DNA in a sample. During Phase I of this project, IA demonstrated the feasibility of monitoring DNA hybridization in real time using an evanescent fiber-...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/01 - 09/30/02

Understanding the mechanisms by which chemical compounds and drugs interact with both the aryl hydrocarbon receptor (AhR) and estrogen receptor (ER) signaling pathways is important both for identifying potential environmental and endocrine disruptors and for screening compounds for therapeutic use. The existence of cross-talk between AhR and ER ...

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