Flow, Inc.

Portland, OR 97239
8 Employees

SBIR Award Summary

Total Number of Awards 9
Total Value of Awards $3.07MM
First Award Date 01/15/91
Most Recent Award Date 09/01/03

Key Personnel

Last Name Name Awards Contact
Makler Michael T. Makler MD 7
Piper Robert C. Piper MD 1
Nakler Michael T. Nakler MD 1

9 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/03 - 08/31/04

DESCRIPTION (provided by applicant): The Diagnosis of Malaria is routinely performed by microscopy of blood smears. However, in both developing countries and developed countries adequate expertise is often limited. Furthermore, this method is quite time-consuming. Flow Inc. has developed a product called the OptiMALr assay, which is an immunochr...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/03

DESCRIPTION (provided by applicant): The Diagnosis of Malaria is routinely performed by microscopy of blood smears. However, in both developing countries and developed countries adequate expertise is often limited. Furthermore, this method is quite time-consuming. Flow Inc. has developed a product called the OptiMALr assay, which is an immunochr...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/15/00 - 01/14/02

The current configuration of the OptiMAL(R) immuno-assay for malaria relies on antibodies generated to P. falciparum LDH. Some of these antibodies recognize all species of human malaria while others are more selective recognizing the falciparum pLDH isoforms specifically. These antibodies when used in combination can differentiate between P. fal...

Phase 2 SBIR

Agency: Army
Topic: A96-141
Budget: 01/30/98 - 01/30/00

Over 2 billion people are at risk of malaria infection worldwide. The availability of rapid and reliable diagnostic test will be an important tool in controlling malaria. Previously, we have developed two diagnostic tests that are based on the detection of Plasmodium Lactate Dehydrogenase. The OptiMALr dipstick test is portable, easy to run, ...

Phase 1 SBIR

Agency: Army
Topic: A96-141
Budget: 11/15/96 - 05/15/97

Phase 2 SBIR

Agency: Army
Topic: A93-247
Budget: 03/24/95 - 08/23/96

We have developed a rapid and quantitative method for the detection of all species of malarial parasites that infect humans. The assay is based on a patented process that can specifically measure Plasmodium sp. lactate dehydrogenase (pLDH). The assay is reproducible and has been standardized with the use of recombinantly expressed pLDH. The s...

Phase 1 SBIR

Agency: Army
Topic: A93-247
Budget: 02/09/94 - 08/08/94

Phase 2 SBIR

Agency: Army
Topic: A90-421
Budget: 05/01/92 - 04/30/94

The detection of drug resistant forms of Plasmodium falciparum has traditionally required a 24-48 hr culture period with analysis conducted by microscopically measuring the level of parasitemia for each test point. It is our intent to modify this procedure to allow earlier detection of the drug resistnat form of the parasite and to permit this ...

Phase 1 SBIR

Agency: Army
Topic: A90-421
Budget: 01/15/91 - 07/15/91