Integrated Genomics, Inc.

2201 West Campbell Drive,
Chicago, IL 60612
http://integratedgenomics.com
92 Employees

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $1.95MM
First Award Date 07/23/99
Most Recent Award Date 09/03/02

Key Personnel

Last Name Name Awards Contact
Vonestin Dr. Veronika Vonestin 1
Demuth Mr. Ronald Demuth 1
Lapidus Dr. Alla Lapidus 3 Message
Osterman Dr. Andrei Osterman 1 Message
Nikolsky Dr. Yuri Nikolsky 2 Message
Fonstein Michael Fonstein 3

7 Awards Won

Phase 2 STTR

Institution: Keck Graduate Institute

Agency: Army
Topic: ARMY01-T005
Budget: 09/03/02 - 09/02/04

Pichia pastoris is a budding yeast used by hundreds of academic and industrial researchers to synthesize a variety of eukaryotic recombinant proteins. P. pastoris is also a model system used to investigate certain areas of eukaryotic cell biology, such as peroxisome biogenesis and degradation, and Golgi organization. The goals of this project a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/02 - 05/31/03

DESCRIPTION (provided by applicant): In completing Phase I of this grant, Integrated Genomics has produced an almost complete genomic sequence of Fusobacterium nucleatum (ATCC25586), leaving only 15 gaps. We have also assigned functions to ORFs using our propriety ERGO IM genomic analysis softwar...

Phase 1 STTR

Institution: Keck Graduate Institute

Agency: Army
Topic: ARMY01-T005
Budget: 11/26/01 - 05/25/02

The overall goal of Phase I is to generate preliminary sequence, functional, and pathway data for Pichia pastoris and to use that information to develop a strategy for strain improvement in Phase I This process will involve the construction of a highly random plasmid library and generation of 30,000 sequencing reactions. Assembly of the contigs ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/01 - 05/31/02

DESCRIPTION (provided by applicant): In completing Phase I of this grant, Integrated Genomics has produced an almost complete genomic sequence of Fusobacterium nucleatum (ATCC25586), leaving only 15 gaps. We have also assigned functions to ORFs using our propriety ERGO IM genomic analysis softwar...

Phase 2 STTR

Institution: University of Illinois, Chicago

Agency: Defense Advanced Research Projects Agency
Topic: ST99-002
Budget: 05/22/01 - 08/30/02

Comparative genomics is an efficient approach to characterize a range of pathogenic properties, from sporulation and pathogenicity factors to the evolution of multi-drug resistance caused by high affinity transport and ion efflux pump systems. IG's WIT-ProTM and "Informatics Workbench" are an optimal system for such studies. In Phase I, we compl...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/15/00 - 10/14/00

DESCRIPTION (Adapted from Applicant's Abstract): Sequencing and analysis of bacterial genomes has become routine in the development of diagnostics, drug targets and improved production strains. Problems with this approach include: (1) unassignable, hypothetical ORFs, comprising 25-50 percent of an average genome;...

Phase 1 STTR

Institution: University of Chicago

Agency: Defense Advanced Research Projects Agency
Topic: ST99-002
Budget: 07/23/99 - 09/22/00

The goal of the proposed research is to provide a biologically rational approach to detection of Bacillus anthracis and protection from its toxicity. The basis of the approach is extensive sequencing of the genomic DNA, including plasmids, of B. anthracis (two strains of 78 known) as well as the genome of B. cereus, the closest known relative. ...