Cambridge Scientific, Inc.

CAMBRIDGE SCIENTIFIC, INC., 180 FAWCETT ST
Cambridge, MA 02138
17 Employees

SBIR Award Summary

Total Number of Awards 64
Total Value of Awards $7.91MM
First Award Date 01/01/88
Most Recent Award Date 07/01/04

Key Personnel

Last Name Name Awards Contact
Trantolo Dr. Debra J. Trantolo 42 Message
Gresser Joseph D. Gresser 16
Wise Donald L. Wise PhD 4 Message
Gressor Joseph Gressor 1
Hile David D Hile 5

64 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/04 - 06/30/05

DESCRIPTION (provided by applicant): In order to expand upon the clinical utility of bone replacement materials, Cambridge Scientific, Inc proposes to develop a biodegradable bone graft extender that has the ability to increase the working volume of autograft without compromising its inductive capacity of autograft Biodegradable extenders would...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/04 - 09/30/04

DESCRIPTION (provided by applicant): Spinal fusion is the most common type of bone grafting procedure. Despite the continuing evolution of devices designed to aid in interbody fusion, nonunion remains problematic. Stability of vertebral segments relies on solid bony fusion across the fusion site. In a typical process, autologous bone, the "gold ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/03 - 06/30/04

DESCRIPTION (provided by applicant): In order to expand upon the clinical utility of bone replacement materials, Cambridge Scientific, Inc proposes to develop a biodegradable bone graft extender that has the ability to increase the working volume of autograft without compromising its inductive capacity of autograft Biodegradable extenders would...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/03

DESCRIPTION: Many new polymer systems are being developed to accommodate biomaterial needs bone reconstruction. However, despite significant advances in the development of newer tissue engineering technologies to better approximate the complex three-dimensional nature of complex tissue equivalents, it has remaine...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-AI-02-05
Budget: 08/01/02 - 03/31/04

DESCRIPTION (provided by applicant): Mucous membranes are the primary routes of entry for a variety of disease carrying agents, including anthrax. Many human pathogens enter and replicate at the mucosal surface before causing systemic infection. It is particularly important to curtail infection at the mucosal surface before persistent infectio...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/02 - 07/31/04

Trauma, oncologic surgery, and congenital disorders often leave patients with large bony defects that require reconstruction. Autografts and allografts are used in current bone graft procedures to repair defects. However, each has clinical drawbacks. The proposed bioresorbable bone graft substitute is made from the unsaturated polyest...

Phase 2 SBIR

Agency: Office of the Secretary of Defense
Topic: OSD00-HP02
Budget: 06/04/02 - 06/04/04

The goal of the Phase II project will be to optimize a PLGA form for clinical trials based on characterization of the dose/response of the particulate in small and large animal models. The particular challenge in moving a DNA/PLGA formulation through the preclinical stages to clinical trials lies in the translation of dose/response information f...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/29/01 - 09/30/02

Acute and chronic liver dysfunction cause approximately 30,000 deaths yearly. Limited supplies of donor organs allow only about 3000 transplants per year. Techniques for temporary liver function replacement (partial transplantation, extracorporeal methods including cross circulation, exchange transfusion, perfusion) are minimally successful. A p...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/07/01 - 09/30/02

The overall objective of this grant application is to employ nanoparticle technology to improve the ability of biopolymeric scaffolds to support ridge reconstruction implants as consolidation of concurrently used bone grafts occurs. The hypothesis of the investigators is...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/01 - 09/30/02

DESCRIPTION: In periodontal ridge reconstruction and subsequent implant fixation, the challenge is to fill bony voids with a graft material, which will maintain the volume and shape of the grafted area and support the structural integrity of the site throughout the course of new bone regeneration. The objecti...

Load More