Chesapeake Perl, Inc.

8510A Corridor Road
Savage, MD 20763
http://www.chesapeakeperl.com
17 Employees

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $4.48MM
First Award Date 05/14/01
Most Recent Award Date 09/17/12

Key Personnel

Last Name Name Awards Contact
Chase Ms. Terry Chase 2 Message
Beek Dr. Nikolai Beek 2 Message
Buchman George Buchman 3 Message
Balcerzak Robert Balcerzak 2 Message

7 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-10-286
Budget: 09/17/12 - 03/31/13

DESCRIPTION (provided by applicant): Project Summary: Lung cancer is the leading cause of cancer death in the United States and is responsible for more deaths each year than breast, prostate, colon, hepatic, renal and skin cancers combined. Viewed in economic terms, in the United States, the value of life lost from lung cancer deaths in the year...

Phase 2 SBIR

Agency: Department of Energy
Topic: 2009
Budget: 01/01/09 - 12/31/09

Cost effective enzymatic lignin degradation could play a key role in enabling commercially viable processes for producing fuel ethanol from woody feedstocks, such as corn stover, switchgrass, hybrid poplar, willow, loblolly pine, and eucalyptus. This project focuses on the identification, production, and eventual commercialization of one import...

Phase 1 SBIR

Agency: Department of Energy
Topic: 2008
Budget: 01/01/08 - 12/31/08

Cellulose is a highly sustainable global resource with considerable relevance to bio-ethanol production. Lignocellulose is a naturally occurring complex of plant-derived materials that includes the hydrophilic sugar polymers cellulose and hemicellulose, and the hydrophobic organic polymer lignin. Although lignocellulose is one of the most abunda...

Phase 2 SBIR

Agency: Army
Topic: CBD03-106
Budget: 02/13/06 - 10/30/09

The central theme of the proposed research is improvement of the quality of product proteins manufactured in insect larvae. The approach is twofold: create the most favorable conditions for the expressed protein to mature, and create the least favorable conditions for proteolytic breakdown in the insect and through downstream processing. A num...

Phase 1 SBIR

Agency: Chemical and Biological Defense Program
Topic: CBD03-106
Budget: 09/02/03 - 03/02/04

Chesapeake PERL is a contract manufacturing company using the baculovirus expression system for mass production of proteins in lepidopterous insect larvae. PERL's automated in-line insect mass rearing and inoculation systems enables the production of large quantities of complex, biologically fully functional proteins. The baculovirus expressio...

Phase 2 SBIR

Agency: Chemical and Biological Defense Program
Topic: CBD01-101
Budget: 07/31/02 - 07/31/04

Chesapeake PERL, Inc aims to develop baculovirus-based expression in insect larvae from bench-scale to mass manufacturing. The technology platform consists of automated mass insect rearing, and inoculation combined with monitoring of protein expression levels in larvae via a fluorescent reporter. This allows the development of "mass customizat...

Phase 1 SBIR

Agency: Chemical and Biological Defense Program
Topic: CBD01-101
Budget: 05/14/01 - 05/22/02

This proposal develops the basis for a self-tuning expression system exploiting fluorescing insect larvae. Chesapeake PERL, Inc., co-founded by Drs. Bentley and Pham, was formed to exploit insects as host organisms, where the eventual biomanufacturing process is comprised of parallel self-regulating "mini" larval bioreactors. The process is ...