Tissue Testing Technologies, LLC

NORTH CHARLESTON, SC 29406

SBIR Award Summary

Total Number of Awards 9
Total Value of Awards $2.43MM
First Award Date 01/23/15
Most Recent Award Date 09/07/17

Key Personnel

Last Name Name Awards Contact
Brockbank Kelvin G.M. Brockbank 33 Message
CAMPBELL LIA H CAMPBELL 11
Campbell Lia H Campbell 1 Message

9 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 09/07/17 - 02/28/18

Resurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis-induced articular cartilage surface damage. Chondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantation. We h...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-HL-15-008
Budget: 09/01/16 - 02/28/17

This proposal is focused on developing innovative new cryopreservation techniques employing ice-free preservation methods that will lead to the ability to bank complex vascularized tissue and organ grafts. Banking of large or complex tissues, such as limbs, and organs using current tissue banking practices employing conventional cryopreservation...

Phase 1 SBIR

Agency: Defense Health Program
Topic: DHP15-014
Budget: 10/01/15 - 05/01/16

We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instea...

Phase 1 SBIR

Agency: Defense Health Program
Topic: DHP15-013
Budget: 10/01/15 - 05/01/16

The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditio...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 09/01/15 - 08/31/16

DESCRIPTION (provided by applicant): In an effort to reduce the use of animals for toxicity testing, companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test. This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 04/10/15 - 03/31/16

DESCRIPTION (provided by applicant): There is an inadequate supply of donated human soft tissues for a variety of surgical applications. Use of the patient's own tissues is often effective but is associated with morbidity or not available due to prior use or inadequate due to pre-existing disease. We have been developing new cryopreservation met...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 04/01/15 - 09/30/15

DESCRIPTION (provided by applicant): There are huge markets for research, diagnostic and clinical applications of naturally occurring and engineered cells, tissues and organs. Strategic assessment of the field has identified the need for better preservation methods because freezing methods of cryopreservation have been shown to damage tissues an...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 02/18/15 - 09/09/15

DESCRIPTION (provided by applicant): Storage of cells for many researchers simply involves addition of 10% DMSO or similar cryoprotectants to cells in suspension, putting them in cryovials and slow cooling to subzero temperaturesf and storage in a mechanical or nitrogen cooled freezer or dewar. As long as viable cells are present upon thawing, c...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 01/23/15 - 08/31/15

DESCRIPTION (provided by applicant): In an effort to reduce the use of animals for toxicity testing, companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test. This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological...