Denovx, LLC

Streamwood, IL 60107

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $1.69MM
First Award Date 01/10/15
Most Recent Award Date 09/01/17

Key Personnel

Last Name Name Awards Contact
BOND ANDREW H. BOND 4

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 09/01/17 - 08/31/18

The goal of this Phase II grant is to expand the Phase I demonstration of improvements to protein crystallization achieved using engineered nucleation surfaces to other high impact targets that include proteins involved in antibiotic resistance and membrane proteins. The role of crystallography in establishing the structure of biological mac...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 05/01/16 - 01/31/17

? DESCRIPTION (provided by applicant): Poor water solubility of active pharmaceutical ingredients (APIs) increasingly poses challenges to drug development, with >70% of new APIs suffering from this issue. Co crystallization is a novel strategy for overcoming these challenges particularly for those APIs that are not readily derivatized with h...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 04/01/16 - 09/30/16

? DESCRIPTION (provided by applicant): Drug shortages negatively affect Public Health by causing treatment delays, medication errors, and by increasing healthcare costs from the need for ad hoc patient management strategies to cope with the shortage. Continuous flow crystallization, a process in which crystalline material is generated under...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 01/10/15 - 07/09/15

DESCRIPTION (provided by applicant): The ability to crystallize proteins for structural biology remains quite challenging, with realized protein crystallization/structure determination success rates hovering around 3%. DeNovX is developing rationally designed nucleation surfaces and thermal methods that enhance success rates and reproducibility ...