Medical Guidance Systems, LLC

Saint Louis, MO 63108

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $667K
First Award Date 09/26/14
Most Recent Award Date 09/19/16

Key Personnel

Last Name Name Awards Contact
HALLAHAN DENNIS E. HALLAHAN 2
ROTI ROTI JOE ROTI 1

3 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 09/19/16 - 08/31/17

Poor prognosis cancers including cancers of the lung and glioblastoma show robust overexpresion of Tax Interacting Protein-1 (TIP1). The proposed research is a novel approach to cancer drug development in which we target this chaperone protein that binds to signal transduction proteins that enhance cell viability following cytotoxic therapy. Str...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 03/01/16 - 02/28/17

? DESCRIPTION (provided by applicant): The proposed research is the study of new paradigms in both the treatment of cancer and cancer drug development. This platform technology will markedly expand the number of cancer specific surface receptors and antigens that can be targeted for drug delivery using peptide ligands. The general principle o...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 09/26/14 - 08/31/15

DESCRIPTION (provided by applicant): Poor prognosis cancers such as lung cancer, glioblastoma, pancreatic cancer and others have 3 year survival rates that range from 1%-15%. Recent advancements in the development of therapeutic antibodies have shown promise in other cancers such as breast, head and neck, and colon cancer. The limitations in...