Bioinvenu Corporation

EAST HANOVER, NJ 07936

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $1.38MM
First Award Date 09/30/13
Most Recent Award Date 04/01/17

Key Personnel

Last Name Name Awards Contact
Eishingdrelo Haifeng Eishingdrelo 4

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-172
Budget: 04/01/17 - 03/31/18

Project Summary In addition to well-documented G protein?dependent and ?-arrestin-dependent GPCR signaling pathways, other cellular effectors are recruited to GPCRs. Signal adaptor protein 14-3-3 is one of such cellular effectors engaged with GPCRs. 14-3-3 proteins are ubiquitously expressed in cells, but their highest expression is found in the...

Unknown

ConProject-001

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-172
Budget: 04/01/17 - 03/31/18

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-172
Budget: 04/15/16 - 03/31/17

? DESCRIPTION (provided by applicant): It is now clear that GPCR signaling is pluridimensional. Defining mechanisms for receptor signaling pathways is essential for understanding many aspects of cell biology, as well as for effectively targeting signaling pathways for drug discovery. Ligands of receptors do not activate all pathways equally b...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-081
Budget: 09/30/13 - 07/31/14

DESCRIPTION (provided by applicant): We plan to develop novel tools for assessing GPCR ligands modulating G-protein-dependent and ?-arrestin- dependent ERK signaling pathways. Many GPCRs display a phenomenon in which different ligands can differentially activate different signaling pathways via the same receptor. It has become clear that single ...