Nymirum, Inc.

Ann Arbor, MI 48103

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $2.15MM
First Award Date 08/01/13
Most Recent Award Date 08/01/17

Key Personnel

Last Name Name Awards Contact
Pape Michael Edward Pape 4
STELZER ANDREW CORBET STELZER 1

5 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 08/01/17 - 07/31/18

Project Summary Abstract The pharmaceutical and biotech industries are targeting various RNA classes to develop new drugs. MicroRNAs (miRNAs) participate in widespread regulation of cell function and contribute to a spectrum of human diseases, especially cancer, making miRNAs a drug-target class of particular interest. Due to delivery issues and...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 04/01/16 - 03/31/17

DESCRIPTION (provided by applicant): The central dogma of molecular biology has undergone a significant revision where RNAs have emerged as important regulators of cell activity. Astonishingly, as much as 80% of human DNA is transcribed into RNA as recently reported by the Encyclopedia of DNA Elements (ENCODE) consortium. New classes of RNA are ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 04/15/15 - 03/31/16

DESCRIPTION (provided by applicant): The central dogma of molecular biology has undergone a significant revision where RNAs have emerged as important regulators of cell activity. Astonishingly, as much as 80% of human DNA is transcribed into RNA as recently reported by the Encyclopedia of DNA Elements (ENCODE) consortium. New classes of RNA are ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 07/05/14 - 01/04/15

DESCRIPTION (provided by applicant): The central dogma of molecular biology has undergone a significant revision where RNAs have emerged as important regulators of cell activity. Astonishingly, as much as 80% of human DNA is transcribed into RNA as recently reported by the Encyclopedia of DNA Elements (ENCODE) consortium. New classes of RNA are ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 08/01/13 - 07/31/14

DESCRIPTION: Myotonic dystrophy 1 (DM1) is the leading form of adult muscular dystrophy resulting in progressive neuromuscular effects. The disease affects 1 in 6000 people. Nymirum is interested in identifying a small molecule that can be used to slow or eliminate the progression of DM1. The cause of DM1 is the expansion of a CUG RNA sequence ...