Axiomx, Inc.

Branford, CT 06405

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $1.89MM
First Award Date 07/15/13
Most Recent Award Date 09/01/15

Key Personnel

Last Name Name Awards Contact
Weiner Michael P Weiner 6

6 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 09/01/15 - 08/31/16

DESCRIPTION (provided by applicant): The most commonly used method for generating antibodies is through immunization of animals. However, this method is generally low-throughput, expensive, time-consuming, and the antibodies generated are not always renewable. Recombinant antibodies (rAb), like single chain variable fragments (scFv), have many a...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 06/01/15 - 03/31/16

DESCRIPTION (provided by applicant): Current methods for converting an antibody fragment (for example, scFv, Fab, Fab', etc.) involves subcloning from an M13 phagemid or yeast display vector by either restriction enzyme digestion or PCR, followed by ligation into 1 or more vectors to produce the heavy and light chains, transformation into E. co...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 02/01/15 - 10/31/15

DESCRIPTION (provided by applicant): Although tyrosine phosphorylation is an important controlling element in cell signaling, no tRNA suppressor for phosphotyrosine (pTyr) incorporation has yet been made. We propose to use directed molecular evolution of several aminoacyl tRNA synthetases (aaRSs) to identify mutations that enable binding of pTyr...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 09/30/14 - 08/31/15

DESCRIPTION (provided by applicant): Site-specific binding of proteins to DNA plays an important role in cell development, cell signaling, the cell cycle, and diseases such as cancer. There are two overarching goals to this proposal: (1) to develop a means for the identification of proteins bound to specific DNA sequences, and (2) to develop a b...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/15/14 - 06/14/15

DESCRIPTION (provided by applicant): The overarching goal of Phase I is to produce a method that will generate, identify and clone a catalog of protein-protein interactions in a single rapid experiment. In this proposal we will model the technology using antibody-antigen interactions. Recombinant antibody libraries against a proteome could be pr...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 07/15/13 - 07/14/14

DESCRIPTION: We intend to refine the affinity-reagent discovery process so that it is not only cheaper and faster than currently possible, but also so that we produce reagents that are more versatile and useful than current monoclonal antibodies. We propose to use in vitro combinatorial recombination of pre-defined synthetic complementarity dete...