Protabit LLC

PASADENA, CA 91106

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $3.79MM
First Award Date 01/01/12
Most Recent Award Date 01/01/17

Key Personnel

Last Name Name Awards Contact
Olafson Barry D. Olafson 12 Message
Mayo Stephen Mayo 1 Message
Olafson Barry D Olafson 2 Message

10 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 01/01/17 - 12/31/17

? DESCRIPTION (provided by applicant): Monoclonal antibodies and other protein-based therapeutics represent a $100+ billion and growing market with broad applications in the treatment of cancer, metabolic diseases, and other human disorders. Thus, any technology that facilitates the discovery of useful protein variants will have a major impac...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 01/01/17 - 12/31/17

? DESCRIPTION (provided by applicant): Engineered proteins such as therapeutic antibodies, specialized enzymes for drug manufacturing, and proteins used to identify new small molecule drugs are making significant contributions to improve health care. Protein therapeutics alone represent a $100+ billion market that is rapidly growing and has ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 06/01/16 - 11/30/16

? DESCRIPTION (provided by applicant): Engineered proteins such as therapeutic antibodies, specialized enzymes for drug manufacturing, and proteins used to identify new small molecule drugs are making significant contributions to improve health care. Protein therapeutics alone represent a $100+ billion market that is rapidly growing and has b...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 01/01/16 - 12/31/16

? DESCRIPTION (provided by applicant): Monoclonal antibodies and other protein-based therapeutics represent a $100+ billion and growing market with broad applications in the treatment of cancer, metabolic diseases, and other human disorders. Thus, any technology that facilitates the discovery of useful protein variants will have a major impac...

Phase 2 STTR

Institution: California Institute of Technology

Agency: National Science Foundation
Topic: BT
Budget: 09/15/15 - 08/31/17

The broader impact/commercial potential of this Small Business Innovation Research Phase II project will combine computational protein engineering (CPE) software, tools and methods into a "platform technology" that enables new products and technologies in a wide range of scientific areas, including industrial enzymes, pharmaceuticals, therapeuti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 12/01/14 - 05/31/15

DESCRIPTION (provided by applicant): Monoclonal antibodies and other protein-based therapeutics represent a $100+ billion and growing market with broad applications in the treatment of cancer, metabolic diseases, and other human disorders. Thus, any technology that facilitates the discovery of useful protein variants will have a major impact in ...

Phase 1 STTR

Institution: Northwestern University

Agency: National Science Foundation
Topic: BC-2013
Budget: 01/01/14 - 12/31/14

This Small Business Technology Transfer Phase I project aims to engineer enzyme variants that will facilitate the complete bioconversion of methane into fuels and high-value chemicals such as isobutanol and 1,4-butanediol. The abundance and low cost of natural gas has stimulated interest in developing biosynthetic pathways to achieve these conve...

Phase 1 STTR

Institution: California Institute of Technology

Agency: Department of Energy
Topic: 12B-2014
Budget: 01/01/14 - 12/31/14

The reaction catalyzed by dihydroxyacid dehydratase is a key bottleneck in the biosynthesis of isobutanol from glucose, caused in part by extremely inefficient maturation of the catalytically essential Fe-S cofactor (~1%) when the dehydratase is recombinantly expressed. One strategy to relieve this bottleneck is to replace this complicated, ener...

Phase 1 STTR

Institution: California Institute of Technology

Agency: National Science Foundation
Topic: AS-2013
Budget: 01/01/13 - 12/31/13

This Small Business Technology Transfer (STTR) Phase I project aims to apply computational protein design (CPD) to engineer polysaccharide monooxygenases (PMOs) for improved thermostability, so that a cocktail of PMOs and key cellulases will more efficiently convert lignocellulolosic biomass to fermentable sugars. The objectives of Phase I are t...

Phase 1 SBIR

Agency: National Science Foundation
Topic: BC-2012
Budget: 01/01/12 - 12/31/12

This Small Business Innovation Research Phase I project aims to apply Protabit?s state-of-the-art computational protein design (CPD) platform to engineer a more thermostable and cost-effective set of lignocellulosic enzymes for converting biomass to simple sugars. CPD is an innovative technology that yields enzymes with novel or enhanced propert...

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