Genvec, Inc.

GAITHERSBURG, MD 20878
http://www.genvec.com
100 Employees

SBIR Award Summary

Total Number of Awards 39
Total Value of Awards $11.5MM
First Award Date 05/01/03
Most Recent Award Date 05/05/17

Key Personnel

Last Name Name Awards Contact
Bruder Dr. Joseph Bruder 10 Message
King C. Richter King 7
Einfeld David A Einfeld 1
Wei Lisa L Wei 7
Mcvey Duncan L Mcvey 5
Brough Douglas E. Brough 3
Gall Jason Gall 6

39 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-16-303
Budget: 05/05/17 - 05/04/18

Project Summary The exceptional promise of gene therapy for hemophilia has been shown in recent studies that result in long term correction of factor IX deficiency, via hepatic transduction with an adeno-associated vector (AAV). In spite of this watershed event in the history of the gene therapy field, there presently exist barriers to the full...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-123
Budget: 06/01/13 - 05/31/14

DESCRIPTION (provided by applicant): RSV is the leading viral cause of lower respiratory illness and hospitalization in young children, yet there isn't an approved vaccine. The vast majority of children infected with RSV suffer from a mild upper respiratory tract infection;however, severe lower respiratory infection develops in 20-30% of RSV-inf...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-123
Budget: 04/01/13 - 03/31/14

DESCRIPTION (provided by applicant): The development of an effective malaria vaccine is a high global health priority. Malaria is the most burdensome parasitic disease of man, exacting an estimated toll of 863,000 deaths and 243 million clinical cases per year. There is an urgent need for a safe and effective malaria vaccine. An abundance of dat...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-123
Budget: 06/01/12 - 05/31/13

DESCRIPTION (provided by applicant): RSV is the leading viral cause of lower respiratory illness and hospitalization in young children, yet there isn't an approved vaccine. The vast majority of children infected with RSV suffer from a mild upper respiratory tract infection;however, severe lower respiratory infection develops in 20-30% of RSV-inf...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-123
Budget: 04/01/12 - 03/31/13

DESCRIPTION (provided by applicant): The development of an effective malaria vaccine is a high global health priority. Malaria is the most burdensome parasitic disease of man, exacting an estimated toll of 863,000 deaths and 243 million clinical cases per year. There is an urgent need for a safe and effective malaria vaccine. An abundance of dat...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 08/01/11 - 07/31/13

DESCRIPTION (provided by applicant): Adenovirus vectors (Advectors) designed to express an antigenic gene have shown great promise as vaccines. Although GenVec and other groups have constructed numerous Advectors expressing a variety of antigens a substantial subset of antigen genes have been found to be inhibitory to Advector construction and p...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 08/01/10 - 07/31/11

DESCRIPTION (provided by applicant): Adenovirus vectors (Advectors) designed to express an antigenic gene have shown great promise as vaccines. Although GenVec and other groups have constructed numerous Advectors expressing a variety of antigens a substantial subset of antigen genes have been found to be inhibitory to Advector construction and p...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 07/01/10 - 06/30/13

DESCRIPTION (provided by applicant): Malaria is a major threat to world health. Each year, there are 350-500 million clinical cases and greater than one million deaths due to malaria, primarily of children in sub- Saharan Africa. There is an urgent need for a safe and effective malaria vaccine and the development of such a vaccine is a global he...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 04/01/10 - 03/31/12

DESCRIPTION (provided by applicant): Recent reports indicate that a new strain of adenovirus serotype 14 (Ad14) is causing frequent acute respiratory disease (ARD) and deaths in otherwise health people. The overall goal of this SBIR is to generate a vaccine that can protect against Ad14 infection and disease. Our hypothesis is that an Ad14 vecto...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 09/28/09 - 08/31/12

DESCRIPTION (provided by applicant): Metastases are the leading cause of death of most cancer patients. Leveraging the immune system to eliminate micrometastasis has long been attempted with only modest success. One limitation is that the local tumor environment often forms immune barriers that prevent sufficient antigen presentation and thus in...

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