Yahsgs LLC

PO Box 667
Richland, WA 99352
http://www.yahsgs.com
20 Employees

SBIR Award Summary

Total Number of Awards 12
Total Value of Awards $1.75MM
First Award Date 01/01/01
Most Recent Award Date 07/15/08

Key Personnel

Last Name Name Awards Contact
Knepp Mr. Anthony Knepp 1 Message
Wassom John S Wassom 4 Message
Yuracko Katherine L. Yuracko 7 Message
Hewitt William Hewitt 1 Message

12 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 07/15/08 - 07/14/09

DESCRIPTION (provided by applicant): The goal of this Phase I project is to demonstrate the feasibility of advancing prototype software (successfully tested on hepatotoxicity) to (1) achieve accurate toxicological endpoint predictions for multiple human organs, and (2) automate processes thereby reducing user skill requirements. The proposed com...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/07 - 03/30/08

DESCRIPTION (provided by applicant): The high cost ($0.8 - $1.7 billion) and long time frames (about 13 years) required to introduce new drugs to the market contributes substantially to spiraling health care costs and diseases persisting without effective cures. A major factor is the high attrition rate of new compounds failing due to toxicity i...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/06 - 03/31/07

DESCRIPTION (provided by applicant): The high cost ($0.8 - $1.7 billion) and long time frames (about 13 years) required to introduce new drugs to the market contributes substantially to spiraling health care costs and diseases persisting without effective cures. A major factor is the high attrition rate of new compounds failing due to toxicity i...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/05 - 03/31/06

DESCRIPTION (provided by applicant): The high cost ($0.8 - $1.7 billion) and long time frames (about 13 years) required to introduce new drugs to the market contributes substantially to spiraling health care costs and diseases persisting without effective cures. A major factor is the high attrition rate of new compounds failing due to toxicity i...

Phase 1 SBIR

Agency: Air Force
Topic: AF05-073
Budget: 04/29/05 - 01/29/06

The goal of this project is to create bioinformatics software that will rapidly and accurately search and mine proteomics-related information from multiple databases and relate the expression of proteins to upstream or downstream events. The proposed product will link upstream and downstream data to those from multiple biotechnologies (e.g., two...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PAR-03-119
Budget: 09/01/04 - 02/28/06

DESCRIPTION (provided by applicant): User-friendly, intelligent, computer-based data mining tools are critical to fully realizing biomedical and toxicology researchers' effectiveness in uncovering knowledge contained in biomedical and toxicology databases and maximizing cross-scientific benefits. For example, continuing scientific advances are r...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-02-75
Budget: 02/20/04 - 08/31/05

DESCRIPTION (provided by applicant): This project bridges the understanding between physical and chemical principles and genomic/proteomic response by integrating three independent parallel toxicity prediction tools. Each uses computational neural networks (CNNs) and wavelets to rapidly and accurately make pharmaceutical/chemical toxicity pre...

Phase 1 STTR

Institution: Battelle Pacific Northwest Division

Agency: Department of Energy
Topic: 2004
Budget: 01/01/04 - 12/31/04

75180-Researchers in the Genomes to Life program, as well as in other biomedical research programs, need a more effective way to search across the multiple heterogeneous databases that are compiling information approaching petabyte levels. Current approaches are limited because they are based on heuristics and keyword indexing and rely on manua...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/03 - 06/30/03

DESCRIPTION (provided by applicant): YAHSGS' Toxicological Evaluation Neuralnet Tools (TEND is designed to advance the state-of-the-art in the prediction of toxicological end points for new or untested chemicals, drugs, and compounds. TENT deploys computational neural nets (CNN), innovative computational chemistry methods, and modem statistical...

Phase 1 STTR

Institution: University of Wisconsin, Madison

Agency: National Science Foundation
Topic: 2003
Budget: 01/01/03 - 12/31/03

This Small Business Technology Transfer (STTR) Phase I project will address the problem of creating robust and efficient software for the solution of large-scale nonlinear optimization problems. Taking advantage of recent advances in algorithm design, the project will investigate novel versions of both interior-point and active-set methods for n...

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