Intrinsic Lifesciences, LLC

La Jolla, CA 92037

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $7.56MM
First Award Date 09/14/09
Most Recent Award Date 03/06/17

Key Personnel

Last Name Name Awards Contact
Westerman Mark Edward Westerman 10

10 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PAR-14-088
Budget: 03/06/17 - 02/28/18

Project Summary/Abstract Erythroferrone (ERFE), the erythroid regulator of hepcidin has recently been discovered and characterized as a hormone expressed in erythroblasts in the marrow. ERFE responds to erythropoietin (EPO) signaling from the EPO receptors in the marrow that stimulate ERFE synthesis and release into the plasma. ERFE then acts as...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-287
Budget: 09/01/16 - 03/31/17

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of hepcidin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/01/16 - 03/31/17

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of hepcidin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/01/15 - 03/31/16

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of hepcidin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/15/14 - 03/31/15

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of hepcidin...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/01/14 - 03/31/15

DESCRIPTION (provided by applicant): Acute kidney injury (AKI) is a common, severe complication of cardiopulmonary bypass (CPB) assisted surgeries, and include coronary artery bypass grafts, valve replacements, aortic aneurisms, and organ transplants. Elderly patients, diabetics, and chronic kidney disease (CKD) patients, have very high risk of...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/01/13 - 03/31/14

DESCRIPTION (provided by applicant): Acute kidney injury (AKI) is a common, severe complication of cardiopulmonary bypass (CPB) assisted surgeries, and include coronary artery bypass grafts, valve replacements, aortic aneurisms, and organ transplants. Elderly patients, diabetics, and chronic kidney disease (CKD) patients, have very high risk of...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-114
Budget: 04/01/12 - 03/31/13

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in the understanding of the molecular basis or iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of h...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-114
Budget: 04/01/11 - 03/31/12

DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in the understanding of the molecular basis or iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of h...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-114
Budget: 09/14/09 - 09/13/10

DESCRIPTION (Provided by Applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in the understanding of the molecular basis or iron homeostasis and its disorders. The peptide hormone hepcidin has emerged as the master regulator of iron metabolism. Dysregulation of h...

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