Vascular Biosciences

San Diego, CA 92109

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $689K
First Award Date 02/01/08
Most Recent Award Date 08/15/17

Key Personnel

Last Name Name Awards Contact
Komatsu Masanobu Komatsu 1
Ruoslahti Erkki Ruoslahti 1
YU PAUL B YU 1

3 Awards Won

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-16-303
Budget: 08/15/17 - 01/31/18
PI: PAUL B YU

PUBLIC ABSTRACT This project, in response to announcement HLS16-06, describes a development program for CARSKNKDC (CAR), a synthetic cyclic peptide that selectively targets diseased pulmonary vascular endothelium and enhances the therapeutic effect of vasodilator therapies, for the treatment of pulmonary hypertension (PH). PH is a disorder of el...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-10-051
Budget: 08/01/11 - 07/31/13

DESCRIPTION (provided by applicant): The repair of injuries is dominated by a tendency to re-establish tissue continuity rather than restoring the structure of the original tissue. This process results in scarring and fibrosis, which is a major medical problem spanning diseases in all organ systems. This application focuses on a compound that ha...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 02/01/08 - 01/31/10

DESCRIPTION (provided by applicant): Blood normally circulates through the lungs at a relatively low pressure. In pulmonary arterial hypertension (PAH) this pressure is increased, often for unknown reasons. Recent results suggest that the underlying problem in PAH may be the thickening of the muscular layer in the walls of lung arteries. At the ...