Ophysio, Inc.

Miami, FL 33136

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $2.89MM
First Award Date 06/15/12
Most Recent Award Date 09/01/17

Key Personnel

Last Name Name Awards Contact
Dominguez-Bendala Juan Dominguez-Bendala 6
Latta Paul Latta 6
Poo Ramon E. Poo 2
Ricordi Camillo Ricordi 2
PASTORI RICARDO L PASTORI 4

6 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 09/01/17 - 08/31/18

PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type 1 diabetes (T1D). However, the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative/renewable sources of insulin-producing cells. In addition to this therapeutic need, a steady supply of i...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 09/01/17 - 08/31/18

The exocrine (acinar/ductal) compartment of the pancreas has been hypothesized to harbor progenitor cells with the ability to give rise to new b-cells. The activation of such progenitors may potentially result in new b-cell formation through differentiation, rather than reprogramming. We hypothesized that, if pancreatic progenitors existed, they...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 09/02/16 - 08/31/17

PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type 1 diabetes (T1D). However, the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative/renewable sources of insulin-producing cells. In addition to this therapeutic need, a steady supply of i...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 04/01/15 - 03/31/16

DESCRIPTION (provided by applicant): It is believed that emergent stem cell-based therapies are destined to replace islet transplantation in the near future. The first wave of next-generation cell therapeutics for type 1 diabetes (T1D) will likely take the shape of pluripotent stem cell (PSC)-derived pancreatic progenitors (PPs) that mature into...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 05/01/13 - 04/30/14

ABSTRACT Conventional culture vessels are not designed for physiological oxygen delivery. Both hyperoxia and hypoxia - commonly observed when culturing cells and tissues in regular plasticware- have been linked to reduced cellular function and death. An adequate means to provide oxygenation is also critical for stem cell applications in which th...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 06/15/12 - 04/30/13

ABSTRACT Conventional culture vessels are not designed for physiological oxygen delivery. Both hyperoxia and hypoxia - commonly observed when culturing cells and tissues in regular plasticware- have been linked to reduced cellular function and death. An adequate means to provide oxygenation is also critical for stem cell applications in which th...