| Last Name | Name | Awards | Contact | |
|---|---|---|---|---|
| Dominguez-Bendala | Juan Dominguez-Bendala | 6 | ||
| Latta | Paul Latta | 6 | ||
| Poo | Ramon E. Poo | 2 | ||
| Ricordi | Camillo Ricordi | 2 | ||
| PASTORI | RICARDO L PASTORI | 4 |
Phase 2 SBIR
PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type 1 diabetes (T1D). However, the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative/renewable sources of insulin-producing cells. In addition to this therapeutic need, a steady supply of i...
Phase 1 SBIR
The exocrine (acinar/ductal) compartment of the pancreas has been hypothesized to harbor progenitor cells with the ability to give rise to new b-cells. The activation of such progenitors may potentially result in new b-cell formation through differentiation, rather than reprogramming. We hypothesized that, if pancreatic progenitors existed, they...
Phase 2 SBIR
PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type 1 diabetes (T1D). However, the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative/renewable sources of insulin-producing cells. In addition to this therapeutic need, a steady supply of i...
Phase 1 SBIR
DESCRIPTION (provided by applicant): It is believed that emergent stem cell-based therapies are destined to replace islet transplantation in the near future. The first wave of next-generation cell therapeutics for type 1 diabetes (T1D) will likely take the shape of pluripotent stem cell (PSC)-derived pancreatic progenitors (PPs) that mature into...
Phase 2 SBIR
ABSTRACT Conventional culture vessels are not designed for physiological oxygen delivery. Both hyperoxia and hypoxia - commonly observed when culturing cells and tissues in regular plasticware- have been linked to reduced cellular function and death. An adequate means to provide oxygenation is also critical for stem cell applications in which th...
Phase 2 SBIR
ABSTRACT Conventional culture vessels are not designed for physiological oxygen delivery. Both hyperoxia and hypoxia - commonly observed when culturing cells and tissues in regular plasticware- have been linked to reduced cellular function and death. An adequate means to provide oxygenation is also critical for stem cell applications in which th...
