Advirna

Boulder, CO 80305
http://www.advirna.com/

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $2.37MM
First Award Date 08/10/11
Most Recent Award Date 02/01/17

Key Personnel

Last Name Name Awards Contact
Wolfson Alexey Wolfson 10 Message
MCKERRACHER LISA JOAN MCKERRACHER 1

7 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 02/01/17 - 01/31/18

Two of the most promising approaches to cancer immunotherapy are immune checkpoint blockade by monoclonal antibodies and the adoptive transfer of immune cells. The recent successes in treating melanoma with anti-PD1 and anti-CTLA antibodies as well as the extremely successful application of T cells engineered to express the CAR receptor targetin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-HG-11-015
Budget: 09/01/15 - 08/31/16

DESCRIPTION (provided by applicant): Completion of the HGP (human genome program) has opened the 'Genomic Era' in biomedical research and enables functional genomics analysis of various gene elements. The long-term goal of the ENCODE Project is to identify and functionally characterize all of the sequence-based genomic elements. Functional eleme...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/15/14 - 08/31/15

DESCRIPTION (provided by applicant): After neurotrauma, neurons in the central nervous system (CNS) do not regenerate their injured axons. Intrinsic signals that progress with normal neuronal differentiation play a significant role in preventing axon regeneration. Several intrinsic negative regulators of regeneration have been identified through...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-HG-11-015
Budget: 09/01/14 - 08/31/15

DESCRIPTION (provided by applicant): Completion of the HGP (human genome program) has opened the 'Genomic Era'in biomedical research and enables functional genomics analysis of various gene elements. The long-term goal of the ENCODE Project is to identify and functionally characterize all of the sequence-based genomic elements. Functional elemen...

Phase 1 SBIR

Agency: National Science Foundation
Topic: BT-2013
Budget: 01/01/14 - 12/31/14

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to provide researchers with more powerful and affordable tools to study activity of genes inside the living cells. RNA interference (RNAi) is a Noble Prize-winning technology that allows specific silencing of gene expression inside living cells. ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-HG-11-015
Budget: 08/01/12 - 01/31/13

DESCRIPTION (provided by applicant): Completion of the HGP (human genome program) has opened the 'Genomic Era'in biomedical research and enables functional genomics analysis of various gene elements. The long-term goal of the ENCODE Project is to identify and functionally characterize all of the sequence-based genomic elements. Functional elemen...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-050
Budget: 08/10/11 - 12/29/12

DESCRIPTION (provided by applicant): Introduction of small interfering RNAs (siRNAs) into cells with transfection reagents results in efficient gene silencing. Unfortunately, while siRNA-based functional genomics is widely used in vitro, the ability to apply this technology to primary cells and in vivo target validation has been impeded limited ...