Differential Proteomics, Inc.

Natick, MA 01760

SBIR Award Summary

Total Number of Awards 12
Total Value of Awards $2.7MM
First Award Date 04/01/07
Most Recent Award Date 06/01/11

Key Personnel

Last Name Name Awards Contact
Stroobant Paul Stroobant 10
Wrighton Nicholas Wrighton 2
Chlenov Mark Chlenov 2

12 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 06/01/11 - 05/31/12

DESCRIPTION (provided by applicant): Immunoglobulins comprise 30-50% of human plasma proteins, and can show several- fold increased levels in many diseases. "Natural" autoantibodies, presumably part of an immune homeostasis mechanism, may comprise >50% of a healthy individual's plasma. The differential identification of disease-associated antib...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 09/24/10 - 05/31/11

DESCRIPTION (provided by applicant): Immunoglobulins comprise 30-50% of human plasma proteins, and can show several- fold increased levels in many diseases. "Natural" autoantibodies, presumably part of an immune homeostasis mechanism, may comprise >50% of a healthy individual's plasma. The differential identification of disease-associated antib...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 07/01/10 - 06/30/11

DESCRIPTION (provided by applicant): A recent assessment of the capabilities of current proteomics technologies states that "the top proteomics labs can identify and quantify more than 6,000 distinct proteins from individual cells and tissues at a time" and this number is probably close to the maximum number of proteins known in plasma. Strikin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 06/01/10 - 05/31/11

DESCRIPTION (provided by applicant): Immunoglobulins comprise 30-50% of human plasma proteins, and can show several- fold increased levels in many diseases. "Natural" autoantibodies, presumably part of an immune homeostasis mechanism, may comprise >50% of a healthy individual's plasma. The differential identification of disease-associated antib...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 09/25/09 - 06/30/11

DESCRIPTION (provided by applicant): In the United States, cardiovascular disease (CVD) accounts for approximately 1.4 million deaths annually, representing nearly 40% of all deaths. The projected cost of heart disease and stroke for 2007 is $431.8 billion. The discovery of new biomarkers will be critical for much-needed advances in screening, d...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 09/15/09 - 06/30/10

DESCRIPTION (provided by applicant): A recent assessment of the capabilities of current proteomics technologies states that "the top proteomics labs can identify and quantify more than 6,000 distinct proteins from individual cells and tissues at a time" and this number is probably close to the maximum number of proteins known in plasma. Strikin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 06/15/09 - 05/31/10

DESCRIPTION (provided by applicant): Immunoglobulins comprise 30-50% of human plasma proteins, and can show several- fold increased levels in many diseases. "Natural" autoantibodies, presumably part of an immune homeostasis mechanism, may comprise >50% of a healthy individual's plasma. The differential identification of disease-associated antib...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 07/07/08 - 06/30/10

DESCRIPTION (provided by applicant): In the United States, the incidence of prostate cancer accounts for approximately 30,000 male deaths annually (1). Prostate-specific antigen screening can detect early-stage prostate cancer, but it is nonspecific and is not recommended by the Centers for Disease Control and Prevention (2). The discovery of ne...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-28
Budget: 09/21/07 - 09/30/08

Project Summary Differential Proteomics, Inc., is developing a new proteomics technology for comparing the protein composition of biological samples. The technology, Differential Capture Proteomics (DCP), is designed to circumvent serious limitations in the current capabilities of current proteomics technology, notably DCP can identify the prote...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-280
Budget: 09/10/07 - 09/09/10

DESCRIPTION (provided by applicant): In the United States in 2002, over 20 million people had diabetes, which contributed to over 224,000 deaths and the total cost of diabetes was $132 billion. A worldwide epidemic of diabetes is now projected which will have serious healthcare and economic consequences. The discovery of new biomarkers will be v...

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