Rxbio, Inc.

Johnson City, TN 37604

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $717K
First Award Date 08/01/07
Most Recent Award Date 09/17/15

Key Personnel

Last Name Name Awards Contact
Gududuru Veeresh Gududuru 1
Deng Wenlin Deng 2
KHAN SAMINA KHAN 1

4 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 09/17/15 - 08/31/16

DESCRIPTION (provided by applicant): Secretory diarrhea is a leading cause of death worldwide among children under the age of five. Its pathology involves cystic fibrosis transmembrane conductance regulator CFTR, which provides a primary pathway for Cl- secretion. Targeting CFTR to prevent/reduce losses of electrolytes and water is a therapeutic...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-044
Budget: 03/01/15 - 02/29/16

DESCRIPTION (provided by applicant): The looming threat of nuclear attacks and recent non-terrorist related accidents (Fukushima nuclear disaster) has increased national and global attention to the need for medical countermeasures. RxBio has identified a first-in class proprietary small molecule-Rx100 which significantly protects the gut and the...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 06/27/08 - 11/30/08

DESCRIPTION (provided by applicant): Bone marrow and gastrointestinal mucosa are highly sensitive to radiation exposure. Radiation-induced damage to bone marrow and the gastrointestinal tract could be lethal in events such as nuclear accidents or radiation terrorism, depending on radiation doses, exposure rate and quality. No truly satisfactory ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 08/01/07 - 01/31/08

DESCRIPTION (provided by applicant): The goal of this Phase I proposal is to perform lead optimization of a novel small molecular radioprotectant based on the Rx100 scaffold. Rx100, a metabolically stabilized analog of phospholipid growth factor lysophosphatidic acid (LPA), has shown promising results in mice, protecting the gut from radiation-i...