Xhale, Inc.

Gainesville, FL 32608

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $4.71MM
First Award Date 09/01/07
Most Recent Award Date 04/01/15

Key Personnel

Last Name Name Awards Contact
Dennis Donn Michael Dennis 4
Melker Richard J Melker 6
Morey Timothy E Morey 2

10 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-133
Budget: 04/01/15 - 03/31/16

DESCRIPTION (provided by applicant): In HIV pre-exposure prophylaxis (PrEP) trials sub-optimal oral and microbicide adherence has precluded accurate estimation of drug efficacy. Measurement of adherence is a major, unmet challenge. Other objective measures of adherence in microbicide trials have been tested, but none measure the actual use of th...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-133
Budget: 04/01/14 - 03/31/15

DESCRIPTION (provided by applicant): In HIV pre-exposure prophylaxis (PrEP) trials sub-optimal oral and microbicide adherence has precluded accurate estimation of drug efficacy. Measurement of adherence is a major, unmet challenge. Other objective measures of adherence in microbicide trials have been tested, but none measure the actual use of th...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/10/12 - 09/09/13

DESCRIPTION (provided by applicant): Propofol endures as the most popular intravenous (IV) anesthetic due to several favorable characteristics. Anesthesia personnel customarily measure the concentrations in breath of many agents used during surgery including: molecular oxygen to prevent hypoxia, carbon dioxide to assure placement of an endotrach...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 08/01/12 - 07/31/13

DESCRIPTION (provided by applicant): Addiction annually costs America >$500B. Narcotic addiction is especially worrisome since intravenous drug abuse (IVDA) also promotes HIV transmission. Reducing IVDA is critical to lowering the incidence of HIV. Since >75% of IVDA is with opioids, effective treatment of opiate addiction should markedly reduc...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 08/01/11 - 07/31/13

DESCRIPTION (provided by applicant): Among drugs that cause widespread human suffering, none is more destructive than ethanol. The estimated annual cost of ethanol abuse in the United States is $185B. A new breath-based toxicological tool with superior capabilities dedicated to understanding the pharmacokinetics (PK) and pharmacodynamics (PD) of...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 09/01/10 - 08/31/11

DESCRIPTION (provided by applicant): Building on our Phase I achievements, we will design and deploy a handheld, breath-based medication adherence monitoring system (adherence system) to identify adherence for clinical trials. The system consists of a miniature, battery powered gas chromatograph (the device) capable of measuring volatile metabol...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 08/20/10 - 07/31/11

DESCRIPTION (provided by applicant): Among drugs that cause widespread human suffering, none is more destructive than ethanol. The estimated annual cost of ethanol abuse in the United States is $185B. A new breath-based toxicological tool with superior capabilities dedicated to understanding the pharmacokinetics (PK) and pharmacodynamics (PD) of...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 09/01/09 - 08/31/10

DESCRIPTION (provided by applicant): Building on our Phase I achievements, we will design and deploy a handheld, breath-based medication adherence monitoring system (adherence system) to identify adherence for clinical trials. The system consists of a miniature, battery powered gas chromatograph (the device) capable of measuring volatile metabol...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/20/07 - 03/31/09

DESCRIPTION (provided by applicant): Ethanol is one of the most widely consumed drugs with resultant profound consequences to individuals and society. The current methodology used to measure ethanol concentration in breath relies on decades old technology and may limit development of breath analysis to detect not only ethanol with great specifi...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/01/07 - 02/29/08

DESCRIPTION (provided by applicant): Principal Investigator/Program Director (Last, First, Middle): Abstract We propose to design and deploy a handheld breath-based "personal" medication adherence monitoring system (MAMS) which will meet the criteria of the solicitation from the National Institute of Mental Health (NIMH) for "Development of info...

Load More