Vasgene Therapeutics, Inc.

Los Angeles, CA 90033

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $1.66MM
First Award Date 09/17/12
Most Recent Award Date 09/01/14

Key Personnel

Last Name Name Awards Contact
Krasnoperov Valery G Krasnoperov 4 Message

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 09/01/14 - 08/31/15

DESCRIPTION (provided by applicant): During embryonic development, EphB4 and EphrinB2 are both critically required for maturation of newly forming blood vessels. EphrinB2 and is critically required for activation of VEGFR2/3. EphrinB2 is up-regulated in tumor vasculature and loss of EphrinB2 led to arrested tumor angiogenesis and inhibited tumor...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 09/27/13 - 08/31/14

DESCRIPTION (provided by applicant): During embryonic development, EphB4 and EphrinB2 are both critically required for maturation of newly forming blood vessels. EphrinB2 and is critically required for activation of VEGFR2/3. EphrinB2 is up-regulated in tumor vasculature and loss of EphrinB2 led to arrested tumor angiogenesis and inhibited tumor...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/24/12 - 02/28/13

DESCRIPTION (provided by applicant): This is aimed at the pre-clinical development of soluble EphB4-HSA (sEphB4-HSA) and its ultimate commercialization for the treatment of various cancer types. sEphB4-HSA was chosen as a pre-clinical due to better efficacy in direct comparisons in xenograft models. Studies with the sEphB4-HSA fusion protein dos...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/17/12 - 02/28/13

DESCRIPTION (provided by applicant): This is aimed at the pre-clinical development of humanized MAb131 (h131) and its ultimate commercialization for the treatment of various cancer types. H131 was chosen for its ability to induce receptor endocytosis, degradation, and inhibition of endothelial cell tube formation. Studies with the MAb131 and th...