Biostrategies, LC

State University, AR 72467

SBIR Award Summary

Total Number of Awards 11
Total Value of Awards $5.85MM
First Award Date 06/15/10
Most Recent Award Date 09/30/17

Key Personnel

Last Name Name Awards Contact
Radin David Radin 11
Xu Jianfeng Xu 1
Cramer Carole L. Cramer 10
MORELLO ROY MORELLO 1
D'AZZO ALESSANDRA D'AZZO 4
CONDORI JOSE MARCOS CONDORI 1
ACOSTA WALTER ACOSTA 3

11 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 09/30/17 - 07/31/18

The long-term goal of this project is to develop an improved ERT for MPS I patients with innovations that enhance ERT delivery and disease correction in hard to treat organs such as the brain while integrating safety and cost advantages of plant-based bioproduction. MPS I Syndrome is caused by genetic deficiencies in the lysosomal enzyme ?-L-idu...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 09/15/17 - 08/31/18

The goal of this SBIR proposal is to develop an effective enzyme replacement therapy (ERT) for patients suffering from GM1 Gangliosidosis by applying a novel ERT enzyme-lectin fusion delivery strategy developed at BioStrategies LC and by exploiting safety, supply, and cost advantages of a plant-based ERT protein bio-manufacturing system. GM1 Gan...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 07/06/16 - 06/30/17

? DESCRIPTION (provided by applicant): The goal of this proposal is to develop an enzyme replacement therapy (ERT) approach for rare genetic diseases that is effective in mitigating the problem of immune sensitization that has hindered previous ERT technologies. Enzyme replacement therapies remain the most effective treatment for those rare ge...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 07/01/16 - 06/30/17

? DESCRIPTION (provided by applicant): The goal of this SBIR proposal is to develop an effective enzyme replacement therapy (ERT) for Sanfilippo A patients by exploiting safety, supply, and cost advantages of plant-based enzyme bioproduction while integrating novel ERT delivery strategies being development at BioStrategies LC. Sanfilippo A (MP...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 07/15/15 - 06/30/16

DESCRIPTION (provided by applicant): The goal of this SBIR proposal is to develop an effective enzyme replacement therapy (ERT) for Sanfilippo A patients by exploiting safety, supply, and cost advantages of plant-based enzyme bioproduction while integrating novel ERT delivery strategies being development at BioStrategies LC. Sanfilippo A (MPS-II...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 07/01/15 - 06/30/16

DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an improved enzyme replacement therapeutic (ERT) for MPS I that integrates safety and cost advantages of plant-based bioproduction with innovations that enhance ERT delivery and disease correction. MPS I (encompassing Hurler, Hurler/Scheie, Scheie syndromes), t...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 07/01/14 - 06/30/15

DESCRIPTION (provided by applicant): The goal of this proposal is to develop an effective enzyme replacement therapy (ERT) for patients suffering from GM1 Gangliosidosis by integrating a novel protein fusion ERT cell delivery strategy under development at BioStrategies LC and by exploiting safety, supply, and cost advantages of new plant-based ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-088
Budget: 07/01/14 - 06/30/15

The long-term goal of this project is to develop an improved enzyme replacement therapeutic (ERT) for MPS I that integrates safety and cost advantages of plant-based bioproduction with innovations that enhance ERT delivery and disease correction. MPS I (encompassing Hurler, Hurler/Scheie, Scheie syndromes), the most common MPS disease, is caused...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-AR-14-005
Budget: 06/01/14 - 05/31/15

DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an effective protein replacement therapeutic (PRT) for patients affected with rare forms of Osteogenesis imperfecta, OI-VIII (deficiency in prolyl 3-hydroxylase 1;P3H1) and OI-VII (deficiency in cartilage associated protein CRTAP). These PRTs will integrate th...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 04/15/13 - 03/31/14

DESCRIPTION (provided by applicant): The goal of this proposal is to develop an effective enzyme replacement therapy (ERT) for Sanfilippo A patients by exploiting safety, supply, and cost advantages of plant-based enzyme bioproduction while integrating novel ERT delivery strategies being development at BioStrategies LC. Sanfilippo A (MPS-IIIA) i...

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