Encode Bio, Inc.

Pasadena, CA 91103

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $1.25MM
First Award Date 04/07/08
Most Recent Award Date 09/07/12

Key Personnel

Last Name Name Awards Contact
Nowak Mark W Nowak 5
Shiva Nima Shiva 1

6 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/07/12 - 08/31/13

DESCRIPTION (provided by applicant): Modulation of intracellular protein-protein interactions has been - and remains - a challenging goal for the discovery and development of small-molecule therapeutic agents. The concept of using peptides to modulate intracellular processes has been investigated for decades, as peptides play a central role in e...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 06/15/10 - 05/31/12

DESCRIPTION (provided by applicant): Benefits of peptide drugs include lower toxicity and greater efficacy than existing drugs and in some cases, new classes of compounds that are otherwise unavailable. However, the development of a peptide lead to a commercial drug continues to be a very challenging and time consuming process. Peptides generall...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 06/01/09 - 05/31/11

DESCRIPTION (provided by applicant): Excessive platelet aggregation leading to thrombosis and vascular occlusion causes a number of cardiovascular disorders including myocardial infarction and stroke. Extensive efforts have been made in the pharmaceutical industry to develop safe and effective anti-platelet drugs to prevent and treat these medic...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 03/01/09 - 02/28/11

DESCRIPTION (provided by applicant): NF(B mediates most of the biological effects of the cytokine TNF( which plays a critical role in the homeostatic control of the immune system. When NF(B becomes overly active, it can cause inflammatory disorders such as rheumatoid arthritis and Crohn's disease. Presently, one of the only ways to reduce hyper...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-50
Budget: 09/15/08 - 08/31/09

DESCRIPTION (provided by applicant): Protein kinases play a central role in many signaling pathways and are key effectors of cellular functions. Abnormalities in protein kinase activity, either due to changes in enzyme levels or mutations in the kinase structure, are responsible for pathologies. As such, protein kinases inhibitors can potentiall...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 04/07/08 - 10/06/09

DESCRIPTION (provided by applicant): Anemia is a serious health issue for millions of people worldwide. The primary pharmacological treatment for anemia is recombinant erythropoietin ("EPO") injections, making it expensive and inconvenient and limiting its use in a large percentage of patients with anemia. Therefore, an orally-available small mo...