Affomix, Inc.

Branford, CT 06405

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $802K
First Award Date 12/01/07
Most Recent Award Date 07/01/10

Key Personnel

Last Name Name Awards Contact
Weiner Michael P Weiner 5
Kiss Margaret Macris Kiss 1

6 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 07/01/10 - 12/31/11

DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In the to-be-developed method: i) a set of antibodies directed against specific DNA-binding prot...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 03/15/10 - 02/28/12

DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a wide-variety of disorders. We propose to develop a means ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 02/15/10 - 02/14/12

DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of affinity screening process based on emulsion, secretion, and capture, which we term "ESCape"....

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 08/17/09 - 08/16/10

DESCRIPTION (provided by applicant): We propose to develop an inexpensive high-throughput means of selecting and identifying antibodies to both unmodified and modified protein, peptide, and non-peptide antigens. The specific goals of this proposal are to complete a proof-of-concept using aqueous droplets in an oil emulsion for identification an...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 05/05/08 - 05/04/10

DESCRIPTION (provided by applicant): Nearly 20 years ago, partially as a response to leveraging the genomics research the NIH invested in the development of gene array technologies. These `gene chips' enabled great breakthroughs in our understanding of the underlying biological processes that occur in cells and tissues. These increased understan...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 12/01/07 - 11/30/09

DESCRIPTION (provided by applicant): Affomix would like to commercialize antibody chips to enable researchers to study the human proteome. Currently, researchers use gene chips as a surrogate means to estimate the concentration of the vast variety of proteins in cells and tissues. But given the choice, most researchers would prefer to study t...