Pion, Inc.

Woburn, MA 01801

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $1.29MM
First Award Date 08/15/05
Most Recent Award Date 08/01/09

Key Personnel

Last Name Name Awards Contact
Avdeef Alex Avdeef 4

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-023
Budget: 08/01/09 - 07/31/10

DESCRIPTION (provided by applicant): Central nervous system (CNS) - targeting drugs, such as antiretrovirals in the treatment of AIDS, need to cross the blood-brain barrier (BBB) in order to reach their therapeutic receptors inside the brain. A critical issue in the treatment of AIDS is that the HIV-1 virus can reside in hard-to-reach sanctuarie...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-23
Budget: 08/26/08 - 07/31/09

DESCRIPTION (provided by applicant): Central nervous system (CNS) - targeting drugs, such as antiretrovirals in the treatment of AIDS, need to cross the blood-brain barrier (BBB) in order to reach their therapeutic receptors inside the brain. A critical issue in the treatment of AIDS is that the HIV-1 virus can reside in hard-to-reach sanctuarie...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-23
Budget: 09/15/07 - 07/31/08

DESCRIPTION (provided by applicant): Central nervous system (CNS) - targeting drugs, such as antiretrovirals in the treatment of AIDS, need to cross the blood-brain barrier (BBB) in order to reach their therapeutic receptors inside the brain. A critical issue in the treatment of AIDS is that the HIV-1 virus can reside in hard-to-reach sanctuarie...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-04-86
Budget: 08/15/05 - 02/14/06

DESCRIPTION (provided by applicant): We propose the development of a high-throughput analytic tool that can accurately assess passive permeability of drug-like molecules across the blood-brain barrier (BBB), using an artificial membrane measuring technique developed by plON. The parallel artificial membrane permeability assay (PAMPA) will incor...