Apath, LLC

Saint Louis, MO 63141
http://www.apath.com
16 Employees

SBIR Award Summary

Total Number of Awards 25
Total Value of Awards $6.94MM
First Award Date 09/01/99
Most Recent Award Date 09/15/07

Key Personnel

Last Name Name Awards Contact
Olivo Dr. Paul D. Olivo 24 Message
Noueiry Amine Osman Noueiry 1

25 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/15/07 - 08/31/08

DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection is a major cause of liver disease throughout the world. Existing therapies are suboptimal and the search for alternative therapies is imperative. Recent years have seen a tremendous increase in efforts to identify more effective therapies against HCV. These efforts have been ...

Phase 2 SBIR

Agency: Chemical and Biological Defense Program
Topic: CBD05-119
Budget: 03/16/06 - 06/16/08

The goal of this proposal is to find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/06 - 01/31/07

DESCRIPTION (provided by applicant): Influenza virus causes a pandemic disease of the respiratory tract that results in significant human morbidity and mortality. Diagnosis of influenza virus infection during the winter months makes up a large component of the clinical virology workload. The goal of this application is to develop transgenic cel...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PAS-02-149
Budget: 07/01/05 - 06/30/07

DESCRIPTION (provided by investigator): Several viruses in the family Bunyaviridae are significant human pathogens and potential agents of bioterrorism. Vaccines against some of these viruses do exist, but with the exception of ribavarin, there are no broad-spectrum antiviral compounds capable of inhibiting replication of more than one member of...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAS-02-149
Budget: 07/01/05 - 06/30/07

DESCRIPTION (provided by applicant): The goal in this study is to develop a cell-based assay to screen compounds for antiviral activity against certain members of the Togavirus family. We are particularly targeting the more pathogenic encephalitis-causing viruses from the alphavirus genus, such as Venezuelan equine encephalitis virus (VEEV), Eas...

Phase 1 SBIR

Agency: Chemical and Biological Defense Program
Topic: CBD05-119
Budget: 05/16/05 - 12/15/05

The goal of this proposal is find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agen...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/05 - 02/28/06

DESCRIPTION (provided by applicant): Filoviruses include some of the most notorious human pathogens and cause significant morbidity and mortality due to severe hemorrhagic fever syndromes. Unfortunately, very few therapeutic agents are available to treat infections with these viruses. The goal of this application is to use a cell-based assay de...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/05 - 01/31/06

DESCRIPTION (provided by applicant): Influenza virus causes a pandemic disease of the respiratory tract that results in significant human morbidity and mortality. Diagnosis of influenza virus infection during the winter months makes up a large component of the clinical virology workload. The goal of this application is to develop transgenic cel...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PAS-02-149
Budget: 07/15/04 - 06/30/05

DESCRIPTION (provided by investigator): Several viruses in the family Bunyaviridae are significant human pathogens and potential agents of bioterrorism. Vaccines against some of these viruses do exist, but with the exception of ribavarin, there are no broad-spectrum antiviral compounds capable of inhibiting replication of more than one member of...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAS-02-149
Budget: 07/01/04 - 06/30/05

DESCRIPTION (provided by applicant): The goal in this study is to develop a cell-based assay to screen compounds for antiviral activity against certain members of the Togavirus family. We are particularly targeting the more pathogenic encephalitis-causing viruses from the alphavirus genus, such as Venezuelan equine encephalitis virus (VEEV), Eas...

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