Acumen Pharmaceuticals, Inc.

Livermore, CA 94551

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $728K
First Award Date 08/01/05
Most Recent Award Date 09/15/16

Key Personnel

Last Name Name Awards Contact
Krafft Grant Arthur Krafft 2
HEFTI FRANZ F HEFTI 1
KLEIN WILLIAM L KLEIN 1

4 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-15-270
Budget: 09/15/16 - 05/31/17

In the United States in 2015 an estimated 5.3 million people suffered from Alzheimer?s disease (AD), with as many as 50% being undiagnosed (Alzheimer?s Association 2015). Three stages of AD are proposed (National Institute on Aging and the Alzheimer?s Association 2011): preclinical AD, mild cognitive impairment (MCI) due to AD, and dementia due ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/30/14 - 01/31/15

DESCRIPTION (provided by applicant): In the United States in 2013, 5.2 million people are estimated to suffer from Alzheimer's disease, with as many as 50% being undiagnosed [Alzheimer's Association 2013]. Current diagnostic technologies for Alzheimer's disease are based on the levels of total soluble amyloid beta (Abeta) peptide in plasma and/o...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/15/05 - 02/28/06

DESCRIPTION (provided by applicant): Recent evidence suggests that the primary cause of Alzheimer's disease is the progressive accumulation of neurotpxic oligomeric assemblies of the Abeta 1-42 protein. These neurotoxic oligomeric species are known as ADDLs (Ab-derived diffusible ligands). In Tg2576 AD mice, a transgenic Alzheimer's disease ani...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/05 - 12/31/05

DESCRIPTION (provided by applicant): The molecular and cellular details underlying Alzheimer's disease (AD) are being defined at an accelerating pace, leading to new therapeutic discovery efforts that target reduction of A-beta or ADDLs (A-beta-derived diffusible ligands), the neurotoxic oligomeric assemblies of A-beta 1-42. Elevated ADDL level...