Endoprotech, Inc.

Louisville, KY 40204

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $3MM
First Award Date 05/01/05
Most Recent Award Date 09/01/16

Key Personnel

Last Name Name Awards Contact
Maldonado Claudio Maldonado 6
Bauer Philip Bauer 4
Gobejishvili Leila Gobejishvili 3
TANG XIAN-LIANG TANG 1

7 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 09/01/16 - 08/31/17

? DESCRIPTION (provided by applicant): Alcoholic Liver Disease (ALD) remains a leading cause of death from liver disease in the U.S., and no FDA-approved therapy exists. Abnormal cytokine metabolism is a major feature of ALD. Elevated serum concentrations of tumor necrosis factor (TNF-?) and TNF-?-inducible proinflammatory cytokines/chemokine...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 07/01/16 - 06/30/17

? DESCRIPTION (provided by applicant): According to the CDC in 2013, ischemic heart disease is the leading cause of death worldwide, and in the US approximately 450,000 patients died of ischemic heart disease. It is well established in clinical practice that recanalization of he infarct related artery (IRA) using percutaneous coronary interven...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 09/25/15 - 08/31/16

DESCRIPTION (provided by applicant): Alcoholic Liver Disease (ALD) remains a leading cause of death from liver disease in the U.S., and no FDA-approved therapy exists. Abnormal cytokine metabolism is a major feature of ALD. Elevated serum concentrations of tumor necrosis factor (TNF- ) and TNF- -inducible proinflammatory cytokines/chemokines, su...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 07/25/12 - 06/30/13

DESCRIPTION (provided by applicant): Alcoholic Liver Disease (ALD) remains a leading cause of death from liver disease in the U.S., and there is still no FDA-approved therapy. Abnormal cytokine metabolism is a major feature of ALD. Elevated serum concentrations of tumor necrosis factor (TNF-) and TNF--inducible proinflammatory cytokines/chemokin...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-281
Budget: 09/01/09 - 08/31/11

DESCRIPTION (provided by applicant): Tissue and organ transplantation procedures save and/or improve the lives of hundred of thousands of patients annually in the US. The goal of this research is to develop a local anti-complement therapy for donor organ ex vivo application that will reduce complement-induced injury to the vascular endothelium. ...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 09/01/08 - 08/31/09

DESCRIPTION (provided by applicant): Tissue and organ transplantation procedures save and/or improve the lives of hundred of thousands of patients annually in the US. The goal of this research is to develop a local anti-complement therapy for donor organ ex vivo application that will reduce complement-induced injury to the vascular endothelium. ...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/05 - 10/31/06

DESCRIPTION (provided by applicant): The purpose of this proposal is to provide proof-of-concept that a novel therapy that prevents complement activation could be effective in reducing ischemia reperfusion injury (IRI) in transplanted organs. Complement activation after IRI in transplanted organs is a well-known phenomenon that may be respons...