Potomac Affinity Proteins, LLC

North Potomac, MD 20878

SBIR Award Summary

Total Number of Awards 14
Total Value of Awards $4.68MM
First Award Date 03/01/06
Most Recent Award Date 07/01/16

Key Personnel

Last Name Name Awards Contact
Ruan Biao Ruan 14

14 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 07/01/16 - 06/30/17
PI: Biao Ruan

DESCRIPTION (provided by applicant): Our objective is to develop a Protease Chain Reaction technology (ProCR) that will enable ultra- sensitive and highly-quantitative detection of cancer markers. The basic element of a protease chain reaction is a protease-inhibitor complex. The protease is inactive when bound to the inhibitor but, once freed, ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 07/01/15 - 06/30/17
PI: Biao Ruan

DESCRIPTION (provided by applicant): Our objective is to develop a Protease Chain Reaction technology (ProCR) that will enable ultra- sensitive and highly-quantitative detection of cancer markers. The basic element of a protease chain reaction is a protease-inhibitor complex. The protease is inactive when bound to the inhibitor but, once freed, ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 07/01/14 - 06/30/15
PI: Biao Ruan

DESCRIPTION (provided by applicant): Our objective is to develop a Protease Chain Reaction technology (ProCR) that will enable ultra- sensitive and highly-quantitative detection of cancer markers. The basic element of a protease chain reaction is a protease-inhibitor complex. The protease is inactive when bound to the inhibitor but, once freed, ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 02/01/14 - 01/31/15
PI: Biao Ruan

DESCRIPTION (provided by applicant): Proteomics is a rapidly expanding field but current methodologies remain inadequate for achieving its full potential. The most basic enzymological tool for characterizing proteins is the protease. Proteases are already an essential part of proteomic analysis but more sophisticated tools are needed to identify...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 07/10/13 - 06/30/14
PI: Biao Ruan

DESCRIPTION (provided by applicant): Our objective is to develop a Protease Chain Reaction technology (ProCR) that will enable ultra- sensitive and highly-quantitative detection of cancer markers. The basic element of a protease chain reaction is a protease-inhibitor complex. The protease is inactive when bound to the inhibitor but, once freed, ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 02/01/13 - 01/31/14
PI: Biao Ruan

DESCRIPTION (provided by applicant): Proteomics is a rapidly expanding field but current methodologies remain inadequate for achieving its full potential. The most basic enzymological tool for characterizing proteins is the protease. Proteases are already an essential part of proteomic analysis but more sophisticated tools are needed to identify...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-10-013
Budget: 09/01/12 - 08/31/13
PI: Biao Ruan

SUMMARY Our objective is to develop a protease chain reaction technology (ProCR) which will enable ultra- sensitive molecular detection. A protease chain reaction has four basic components: 1) a protease conjugated to a binding molecule, 2) an unconjugated protease, 3) an inhibitor protein which contains a proteolytic cleavage site and 4) a prot...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 02/01/12 - 01/31/13
PI: Biao Ruan

DESCRIPTION (provided by applicant): Proteomics is a rapidly expanding field but current methodologies remain inadequate for achieving its full potential. The most basic enzymological tool for characterizing proteins is the protease. Proteases are already an essential part of proteomic analysis but more sophisticated tools are needed to identify...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-10-013
Budget: 09/19/11 - 08/31/12
PI: Biao Ruan

DESCRIPTION (provided by applicant): Our objective is to develop a protease chain reaction technology (ProCR) which will enable ultra- sensitive molecular detection. A protease chain reaction has four basic components: 1) a protease conjugated to a binding molecule, 2) an unconjugated protease, 3) an inhibitor protein which contains a proteolyti...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-451
Budget: 02/01/11 - 01/31/12
PI: Biao Ruan

DESCRIPTION (provided by applicant): Proteomics is a rapidly expanding field but current methodologies remain inadequate for achieving its full potential. The most basic enzymological tool for characterizing proteins is the protease. Proteases are already an essential part of proteomic analysis but more sophisticated tools are needed to identify...

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