Boston Biochem, Inc.

Cambridge, MA 02139

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $920K
First Award Date 04/10/06
Most Recent Award Date 08/01/09

Key Personnel

Last Name Name Awards Contact
Lapan Kirsty A Lapan 3

3 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-280
Budget: 08/01/09 - 07/31/10

DESCRIPTION (provided by applicant): Deubiquitinating enzymes play critical regulatory roles in the ubiquitin-proteasome pathway (UPP). Despite their relevance to human disease and interest by pharma as targets for therapeutic development, this diverse class of enzymes is understudied and detailed biochemical data is lacking. Highly purified DUB...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 08/01/08 - 07/31/09

DESCRIPTION (provided by applicant): Deubiquitinating enzymes play critical regulatory roles in the ubiquitin-proteasome pathway (UPP). Despite their relevance to human disease and interest by pharma as targets for therapeutic development, this diverse class of enzymes is understudied and detailed biochemical data is lacking. Highly purified DUB...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-03-45
Budget: 04/10/06 - 10/31/06

DESCRIPTION (provided by applicant): Well-defined and novel ubiquitin derivatives would be invaluable tools for basic research and drug discovery efforts, but these are commercially unavailable. We propose in this Phase I SBIR grant to develop a comprehensive panel of ubiquitin variants, making all combinations of lysine mutations and N-terminal...