Ariavax, Inc.

Gaithersburg, MD 20878

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $774K
First Award Date 05/01/05
Most Recent Award Date 02/01/09

Key Personnel

Last Name Name Awards Contact
Robey Frank A. Robey 3

3 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 02/01/09 - 07/31/10

DESCRIPTION (provided by applicant): The bridging sheet in HIV-1 gp120 connects the inner domain with the outer domain of gp120. Half of the bridging sheet (2/3) is composed of amino acids from the variable segments from the V2 and V3 domains whereas the second half of the bridging sheet, referred to as 20/21, is composed of highly conserved ami...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-04-27
Budget: 09/01/06 - 02/29/08

DESCRIPTION (provided by applicant): Gp160, the major surface protein on HIV, is composed of 2 key subunits, gp120 and gp41. Within either subunit there can be found regions of interest for vaccine development efforts; both gp120 and gp41 contain zones or sub domains that play fundamental biochemical roles in the infection process. There also ar...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/05 - 04/30/06

DESCRIPTION (provided by applicant): 4E10 is a monoclonal antibody that was derived from the B cells of a patient with persistent HIV infections. In vitro and in vivo, 4E10 neutralizes a wide variety of HIV and SHIV strains. As such, an immunogen that elicits 4E10-like antibody responses in humans would be a huge advance toward the goal of desi...