Zuchem, Inc.

Chicago, IL 60612

SBIR Award Summary

Total Number of Awards 20
Total Value of Awards $6.5MM
First Award Date 04/01/05
Most Recent Award Date 04/01/16

Key Personnel

Last Name Name Awards Contact
Dodds David R. Dodds 1
Woodyer Ryan Woodyer 6 Message
Wymer Nathan J Wymer 1
Shepherd Micah Shepherd 4
Aminova Leila Aminova 6
Racine Mike Racine 2 Message
Berardesco Gina Berardesco 2 Message

20 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 04/01/16 - 03/31/17

? DESCRIPTION (provided by applicant): Fucosylation plays an important role in many cellular processes. Fucosylated oligosaccharides in the cell are involved in many biochemical recognition processes, microbial infections, toxin entry, and cancer cell metastasis. These properties make fucosylated molecules valuable for pharmaceutical and dru...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 03/01/16 - 08/31/16

? DESCRIPTION (provided by applicant): The goal of this proposal is to develop a fermentative strategy for the large-scale production of L-fucose and other rare sugars. L-fucose (6-deoxy-L-galactose) is an important hexose deoxysugar found in a variety of organisms attached to an array of macromolecules. These L-fucose containing glycans exhi...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/01/15 - 08/31/16

DESCRIPTION (provided by applicant): The ultimate goal of the proposal presented herein is to use E. coli as whole cell biocatalysts for the production of a wide variety of TDP-deoxysugars including di- and tri-deoxysugars, amino sugars and branched-chain sugars. These specialized activated hexoses are found as important structural components th...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 04/01/15 - 03/31/16

DESCRIPTION (provided by applicant): Fucosylation plays an important role in many cellular processes. Fucosylated oligosaccharides in the cell are involved in many biochemical recognition processes, microbial infections, toxin entry, and cancer cell metastasis. These properties make fucosylated molecules valuable for pharmaceutical and drug dis...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/15/14 - 08/31/15

DESCRIPTION (provided by applicant): The ultimate goal of the proposal presented herein is to use E. coli as whole cell biocatalysts for the production of a wide variety of TDP-deoxysugars including di- and tri-deoxysugars, amino sugars and branched-chain sugars. These specialized activated hexoses are found as important structural components th...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 09/01/14 - 02/28/15

DESCRIPTION (provided by applicant): UDP-GlcNAc and UDP-GalNAc comprise the core structures of glycans in glycoproteins and glycolipids. Oligosaccharides containing N-acetyl-hexosamines involved in various biological process, including microbial infection, toxin entry, cancer cell metastasis. They are the key building blocks for human milk oligo...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 09/15/13 - 03/14/14

DESCRIPTION: Fucosylation plays an important role in much cellular process. Fucosylated oligosaccharides in the cell are involved in various types of biochemical recognition processes and in microbial infections, toxin entry, and cancer cells metastasis. These properties make these carbohydrates valuable for pharmaceutical and drug discovery n...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 07/01/12 - 03/31/13

DESCRIPTION (provided by applicant): The ultimate goal of the proposal presented herein is to use E. coli as whole cell biocatalysts for the production of a wide variety of TDP-deoxysugars including di- and tri-deoxysugars, amino sugars and branched-chain sugars. These specialized activated hexoses are found as important structural components th...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 08/15/10 - 05/31/12

DESCRIPTION (provided by applicant): The overall goal of this proposal is to create a robust one pot, in vitro, multi-gram scale synthesis of activated sugars for drug discovery and biochemical research purposes. Natural product glycosylation is vital for the discovery of new pharmaceutical compounds. While it has been recognized for some time t...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 06/01/10 - 05/31/12

DESCRIPTION (provided by applicant): The overall goal of this proposal is to create a robust one pot, in vitro, multi-gram scale synthesis of activated sugars for drug discovery and biochemical research purposes. Natural product glycosylation is vital for the discovery of new pharmaceutical compounds. While it has been recognized for some time t...

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