Mediomics, LLC

SAINT LOUIS, MO 63124

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $2.53MM
First Award Date 01/01/02
Most Recent Award Date 09/15/17

Key Personnel

Last Name Name Awards Contact
Heyduk Tomasz Heyduk 5
Heyduk Ewa Heyduk 2 Message
Chang Yie-Hwa Chang 1 Message
TIAN LING TIAN 3

10 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 09/15/17 - 03/31/18
PI: LING TIAN

Graves? disease (GD) is the most common cause of hyperthyroidism, accounting for 60 to 80 percent of more than 250 million cases of hyperthyroidism globally. It is an autoimmune disorder caused by thyroid stimulating antibodies (TSAbs), which bind to the thyrotropin (or thyroid-stimulating hormone (TSH)) receptor on the surface of a thyroid cell...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-16-302
Budget: 03/10/17 - 02/28/18
PI: LING TIAN

This proposal aims to develop highly specific, rapid and cost-effective immunoassays to detect Zika virus (ZIKV) infection. ZIKV is a single-stranded RNA virus in the Flaviviridae family that is transmitted to humans through infected mosquitos, blood transfusions, and sexual contact. As of June 2016, around 500,000 Zika Virus disease cases have ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-DA-16-005
Budget: 08/15/16 - 01/31/17
PI: LING TIAN

More than 100 structurally distinct modified nucleosides have been identified, and at least 66 ofthem occur in eukaryotic cells. However, the functional roles of many other covalent RNAmodifications remain poorly characterized or unknown, although they are likely to influence RNAproperties and functions such as RNA stability, trafficking, locali...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-281
Budget: 05/01/10 - 04/30/12

DESCRIPTION (provided by applicant): Detection and quantification of proteins in various biological samples is one of the most important and most often utilized assays with applications in research, medical diagnosis, early disease detection and detection of biological threat agents. While many protein detection methodologies are available (ELIS...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-281
Budget: 09/30/09 - 08/31/10

DESCRIPTION (provided by applicant): Detection and quantification of proteins in various biological samples is one of the most important and most often utilized assays with applications in research, medical diagnosis, early disease detection and detection of biological threat agents. While many protein detection methodologies are available (ELIS...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-281
Budget: 05/01/09 - 04/30/10

DESCRIPTION (provided by applicant): Detection and quantification of proteins in various biological samples is one of the most important and most often utilized assays with applications in research, medical diagnosis, early disease detection and detection of biological threat agents. While many protein detection methodologies are available (ELIS...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-06-21
Budget: 03/01/07 - 02/28/09

DESCRIPTION (provided by applicant): Detection of the presence and the determination of the amount of a specific protein using various techniques utilizing antibodies specific to the target protein are one of the most important tools in biomedical research, medical diagnosis and detection of biological threat agents. These techniques (such as, f...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-06-07
Budget: 09/19/06 - 08/31/09

DESCRIPTION (provided by applicant): Highly multiplexed detection of biological molecules and their activities has been an essential element of modern molecular diagnosis, drug development and research in genomics and proteomics. Well established DNA array methodologies exist which permit highly multiplexed detection of transcripts. Similar meth...

Phase 2 SBIR

Agency: National Science Foundation
Topic: 2004
Budget: 01/01/04 - 12/31/04

This Small Business Innovation Research (SBIR) Phase II project will complete the development of biosensors for detection of heavy metals and acyl-CoA using sequence-specific DNA binding proteins. The presence of the target molecule will be reported by the biosensor as a change in fluorescence signal that could be read using a hand-held battery-...

Phase 1 SBIR

Agency: National Science Foundation
Topic: 2002
Budget: 01/01/02 - 12/31/02

This Small Business Innovation Research Phase I project will develop a new general platform for preparing biosensors for a large number of target molecules. The target molecules for these biosensors will be the compounds (ligands) which regulate DNA binding activity of sequence-specific DNA binding proteins. A large number of such highly-select...

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