Vivo Biosciences, Inc.

Birmingham, AL 35205

SBIR Award Summary

Total Number of Awards 15
Total Value of Awards $4.88MM
First Award Date 09/16/04
Most Recent Award Date 09/22/15

Key Personnel

Last Name Name Awards Contact
Singh Raj K. Singh 11
Klinger Martin M. Klinger 2
VOHRA YOGESH K VOHRA 2

15 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/22/15 - 09/21/17

This SBIR Phase II project is dedicated to complete development and validation of a new Microtumor culture/ assay system which allows robust cellular, molecular and drug efficacy analysis ex vivo. In Phase I, colon and glioma Microtumors were produced with high viability by using patient-derived cells (PDx) and patented 3D HuBiogel culture tech...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/22/15 - 06/21/16

This SBIR project is focused on developing a novel 3D culture system that incorporates a unique HuBiogel scaffold, supports growth/expansion of cancer stem cells (CSCs) and allows precise cellular and molecular analysis. At present, spheroid cultures and synthetic or animal-derived matrices are commonly used by cancer researchers. However, these...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PAR-14-261
Budget: 09/05/14 - 04/14/15

DESCRIPTION (provided by applicant): In this Phase I STTR proposal, our R&D goal is the development and evaluation of a novel functionally-graded biohybrid vascular graft for small diameter (<6 mm) coronary bypass applications. Tissue engineered vascular constructs developed to date have mostly utilized synthetic and animal- derived biomaterials...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 08/01/14 - 07/31/15

DESCRIPTION (provided by applicant): This SBIR project is focused to develop, validate and commercialize an advanced high-throughput anti- tumor drug screening platform (HTS) which employs a new 3D HuBioGEM assay technology. Preclinical drug screening is commonly performed using biochemical and cell-based assay systems. In recent years, more rel...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-12-089
Budget: 04/15/14 - 04/14/15

DESCRIPTION (provided by applicant): In this Phase I STTR proposal, our R&D goal is the development and evaluation of a novel functionally-graded biohybrid vascular graft for small diameter (<6 mm) coronary bypass applications. Tissue engineered vascular constructs developed to date have mostly utilized synthetic and animal- derived biomaterials...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 04/01/13 - 03/31/14

DESCRIPTION (provided by applicant): The overall objective of this SBIR proposal is to develop and commercialize a human 3D or mini- liver bioassay system suitable for real-time analysis of metabolic functions and long-term drug toxicity profiles. At present, liver functions are mostly studied using HepG2 cell line and primary hepatocytes cultur...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 04/10/12 - 03/31/13

DESCRIPTION (provided by applicant): The overall objective of this SBIR proposal is to develop and commercialize a human 3D or mini- liver bioassay system suitable for real-time analysis of metabolic functions and long-term drug toxicity profiles. At present, liver functions are mostly studied using HepG2 cell line and primary hepatocytes cultur...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-006
Budget: 01/19/10 - 12/31/10

DESCRIPTION (provided by applicant): Abstract: The overall goal of this SBIR proposal is to develop and commercialize a new human liver bioassay system for real time, long-term toxicity analysis of chemical agents or drugs in vitro. At present, liver studies are mostly performed using hepatocytes cultured onto synthetic or animal-derived matrice...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 06/03/09 - 05/31/10

DESCRIPTION (provided by applicant): Over 30,000 Americans die each year from prostate cancer, making it the second most lethal form of cancer affecting men in the U.S. Many of these deaths could be prevented if the cancers were detected before the tumor escaped the prostate. Our goal for this research project is to develop a simple blood test t...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-06
Budget: 09/12/07 - 08/31/09

DESCRIPTION (provided by applicant): In our initial R&D effort we successfully demonstrated the feasibility of a novel human biomatrix system (HuBiogel) in designing 3D bioassay system for in vitro examination of tumorigenesis process. The overall goal was and is to develop and commercialize these human bioassay systems. Phase I work definitely ...

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