Rib-x Pharmaceuticals, Inc.

New Haven, CT 06053

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $1.55MM
First Award Date 07/15/03
Most Recent Award Date 05/01/05

Key Personnel

Last Name Name Awards Contact
Sutcliffe Joyce A. Sutcliffe 2
Duffy Erin M. Duffy 1

3 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-03-119
Budget: 05/01/05 - 04/30/06

DESCRIPTION (provided by applicant): We aim to extend and validate computational methods and protocols for treating accurately the interactions among RNA, ions and ligands. Ultimately, we seek tools that are efficient, accurate and useful in a drug discovery framework for identifying small-molecule drugs for RNA therapeutic targets. As research ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/15/05 - 10/31/06

DESCRIPTION (provided by applicant): The specific goal of this proposal is to initiate preclinical studies towards satisfying the requirements for an Investigative New Drug Application (IND) after identifying a compound(s) that could be commercialized and prescribed for the treatment of multidrug-resistant (MDR) Gram-positive hospital-acquired ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/15/03 - 01/14/04

DESCRIPTION (provided by applicant): Rib-X Pharmaceuticals, Inc. has proprietary, high-resolution structural information on how antibiotics bind to the large ribosomal subunit (50S). Using this information in combination with a computational approach that calculates the energetics of RNA-ligand interactions and drug-like properties of these ant...