Last Name | Name | Awards | Contact | |
---|---|---|---|---|
Lo | David D Lo | 3 | ||
Reilly | John F Reilly | 1 | ||
Redwine | Jeffrey Redwine | 1 |
Phase 1 SBIR
DESCRIPTION (provided by applicant): The completion of the mouse genome and the resultant ability to create genetically altered mice have made the mouse the dominant animal model for brain research. However, the limited knowledge of mouse brain connectivity, neurochemistry and physiology, along with existing variations among multiple mouse stra...
Phase 1 SBIR
DESCRIPTION (provided by applicant): There is an ongoing need for improved vaccines and vaccine adjuvants, as many existing vaccine formulations developed using conventional methods still present serious risks to patients without providing increased potency. For example, attenuated organisms still present the risks of serious infection to compr...
Phase 1 SBIR
DESCRIPTION (provided by applicant): Vaccination can be greatly improved by relying on a mechanism used by the mucosal immune system to sample antigens from the small intestine: transcytosis by M cells overlying Peyer's Patches. These specialized cells appear to use specific uptake and transport of microbes and particles to the lymphoid tissue,...
Phase 1 SBIR
DESCRIPTION (provided by applicant): There is an ongoing need for improved vaccines and vaccine adjuvants, as many existing vaccine formulations developed using conventional methods still present serious risks to patients without providing increased potency. For example, attenuated organisms still present the risks of serious infection to compr...
Phase 1 SBIR
DESCRIPTION (provided by applicant): Current behavioral tests to assess the efficacy of putative novel antidepressants lack the necessary validations to allow them to be a robust and reliable in vivo screen. The overall goal of this Fast Track application is to create a novel screening platform to assess the efficacy of putative antidepressants ...