Generation Biotech, LLC

LAWRENCEVILLE, NJ 08648

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $3.53MM
First Award Date 05/01/03
Most Recent Award Date 04/12/17

Key Personnel

Last Name Name Awards Contact
Dapprich Johannes Dapprich 7

7 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-HG-15-033
Budget: 04/12/17 - 03/31/18

This project develops a platform-independent target enrichment technology for the preparation of large (50- 150 kb+) DNA fragments. These are magnetically selected from genomic regions of interest and used directly - without any intermediate amplification step - for next-generation sequencing (NGS). This will allow the direct detection of methyl...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/01/12 - 08/31/13

DESCRIPTION (provided by applicant): This project develops an automated protein preparation technology that uses magnetic microparticles to isolate histones in their native state from specific genomic loci of interest via the chromatin to which they are bound. After extraction, the targeted histones are purified for downstream analysis by quanti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-06
Budget: 09/22/06 - 02/29/08

DESCRIPTION (provided by applicant): Project Summary/Abstract: a) We propose to develop an economical, automated system (BioSprint96) for preparing sub-megabase (250-500kb), and preferably megabase-size genomic DNA from blood or buccal swabs. b) Similar protocols on the same system will enable the targeted extraction of specific, haploid gene re...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/06 - 07/31/09

DESCRIPTION (provided by applicant): Identification of Human Leukocyte Antigens, HLA, for matching of kidney and bone marrow donors and recipients is mandatory for transplantation. Many allele combinations fail to be resolved with current typing methods. Haplotype-Specific Extraction, HSE, establishes haplotypes from an individual patient's samp...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/05 - 07/31/06

DESCRIPTION (provided by applicant): Identification of Human Leukocyte Antigens, HLA, for matching of kidney and bone marrow donors and recipients is mandatory for transplantation. Many allele combinations fail to be resolved with current typing methods. Haplotype-Specific Extraction, HSE, establishes haplotypes from an individual patient's samp...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 07/31/05

DESCRIPTION (provided by applicant): Identification of Human Leukocyte Antigens, HLA, for matching of kidney and bone marrow donors and recipients is mandatory for transplantation. Many allele combinations fail to be resolved with current typing methods. Haplotype-Specific Extraction, HSE, establishes haplotypes from an individual patient's samp...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 07/31/04

DESCRIPTION (provided by applicant): During tissue-typing for transplantation, certain diploid combinations of allele pairs fail to be resolved with current typing methods. Haplotype-Specific Extraction, HSE, establishes haplotypes from individual patient's samples and permits the unambiguous typing of such combinations without knowledge of fami...