Biocatalytics, Inc.

Pasadena, CA 91106

SBIR Award Summary

Total Number of Awards 34
Total Value of Awards $8.65MM
First Award Date 03/01/99
Most Recent Award Date 05/01/07

Key Personnel

Last Name Name Awards Contact
Novick Scott J Novick 5
Zhu Dunming Zhu 1
Rozzell James David Rozzell 16
Kambourakis Spiros Kambourakis 3
Munir Inmar Z Munir 3
Hua Ling Hua 1
Kilgore James L Kilgore 5

34 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 05/01/07 - 10/31/07

DESCRIPTION (provided by applicant): Reduction of carbon-carbon double bonds (C=C) is a fundamental reaction in synthetic organic chemistry. The ability to control the regio-, and stereo-, and chemo selectivity of reduction is of particular importance when designing new hydrogenation catalysts. For example, the chemo-selective reduction of C=C b...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/07 - 01/31/08

DESCRIPTION (provided by applicant): Chiral drugs comprise a steadily increasing percentage of new pharmaceutically-active substances, and their synthesis demands methods that can produce compounds with high stereochemical purity. Chiral alcohols are ubiquitous intermediates in the synthesis of chiral drugs, and the stereoselective reduction of ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/06 - 08/31/07

DESCRIPTION (provided by applicant): Beta-Amino acids are rapidly growing in importance as a key class of pharmaceutical intermediates, with applications in a number of current and future drugs. A cost-effective process for the production of optically pure beta-amino acids will be developed in this project to accommodate the commercial needs f...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/06 - 03/31/07

DESCRIPTION (provided by applicant): Glucuronidation is a major metabolic pathway for the inactivation and detoxification of endogenous and exogenous compounds in the human body. Glucuronides are formed by a super family of uridine diphosphoglucuronosyl transferases (UGTs) that convert a number of lipophilic xenobiotics (drugs, steroids, polluta...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/15/06 - 01/31/07

DESCRIPTION (provided by applicant): Chiral drugs comprise a steadily increasing percentage of new pharmaceutically-active substances, and their synthesis demands methods that can produce compounds with high stereochemical purity. Chiral alcohols are ubiquitous intermediates in the synthesis of chiral drugs, and the stereoselective reduction of ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/06 - 07/31/07

DESCRIPTION (provided by applicant): Abuse of gamma-hydroxybutyrate (GHB) as a recreational drug is becoming increasingly more prevalent due to the general feeling of euphoria it produces when ingested in moderate levels. At higher levels, unconsciousness and coma can result making this the drug of choice in "date-rape" crimes. Because of this, ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/20/05 - 08/31/06

DESCRIPTION (provided by applicant): Beta-Amino acids are rapidly growing in importance as a key class of pharmaceutical intermediates, with applications in a number of current and future drugs. A cost-effective process for the production of optically pure beta-amino acids will be developed in this project to accommodate the commercial needs f...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/05 - 08/31/06

DESCRIPTION (provided by applicant): Nicotinamide cofactor dependent enzymes are increasingly finding use for the synthesis of chiral intermediates for the production of pharmaceuticals. With the increased availability of various oxidoreductases (BioCatalytics, Inc. 2003 catalog, see appendix), and the work on existing processes using amino acid...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/15/05 - 03/31/06

DESCRIPTION (provided by applicant): Glucuronidation is a major metabolic pathway for the inactivation and detoxification of endogenous and exogenous compounds in the human body. Glucuronides are formed by a super family of uridine diphosphoglucuronosyl transferases (UGTs) that convert a number of lipophilic xenobiotics (drugs, steroids, polluta...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 08/31/05

DESCRIPTION (provided by applicant): Nicotinamide cofactor dependent enzymes are increasingly finding use for the synthesis of chiral intermediates for the production of pharmaceuticals. With the increased availability of various oxidoreductases (BioCatalytics, Inc. 2003 catalog, see appendix), and the work on existing processes using amino acid...

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