Panomics, Inc.

Redwood City, CA 94063

SBIR Award Summary

Total Number of Awards 8
Total Value of Awards $2.53MM
First Award Date 09/30/01
Most Recent Award Date 03/01/05

Key Personnel

Last Name Name Awards Contact
Bedford Mark T Bedford 1
Li Xianqiang Jason Li 5
Jiang Xin Jiang 2

8 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/05 - 08/31/05
PI: Xin Jiang

DESCRIPTION (provided by applicant): Breast cancer is caused by the accumulation of genetic and epigenetic changes. The cDNA microarray technology has been widely used for identifying cancer-related changes in gene expression for breast tumor classification and prognosis. However, the information obtained from cDNA microarray analysis is not ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 07/31/05

DESCRIPTION (provided by applicant): Transcription factors (TFs) are a group of proteins that regulate gene expression. In humans, they regulate the expression of about 30,000 genes. Their activities are in turn regulated by a number of different mechanisms including interaction with other transcription factors or co-regulators. Because of the l...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/04 - 06/30/04
PI: Xin Jiang

DESCRIPTION (provided by applicant): Transcription factors (TFs) are cellular proteins responsible for controlling gene expression. Understanding the mechanism underlying the activation of these proteins will help us dissect cellular signaling pathways and determine the relationship between transcription activation and human diseases. Moni...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/03 - 07/31/04

DESCRIPTION (provided by applicant): Transcription factors (TFs) are a group of proteins that regulate gene expression. In humans, they regulate the expression of about 30,000 genes. Their activities are in turn regulated by a number of different mechanisms including interaction with other transcription factors or co-regulators. Because of the l...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/03 - 07/31/04

DESCRIPTION (provided by applicant): Protein domains mediate protein-protein interaction through binding to short peptide motifs in their corresponding ligands. These peptide recognition modules are critical for the assembly of multi-protein complexes. We have arrayed GST fusion protein, with a focus on protein interaction domains, onto nitrocel...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/03 - 07/31/03

DESCRIPTION (provided by applicant): Transcription factors (TFs) are a group of proteins that regulate gene expression. In humans, they regulate the expression of about 30,000 genes. Their activities are in turn regulated by a number of different mechanisms including interaction with other transcription factors or co-regulators. Because of the l...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/02 - 03/31/03

To understanding the role of a gene of interest and use it for gene therapy we need a way to control its expression in mammalian cells. The usual approach is to modulate transcription/ Accumulation of mRNA commonly require hours. We will develop a system based on the inducible translational frameshifting that can shorten the lag time from minute...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/01 - 09/29/02

Most regulatory proteins turn over rapidly. We will develop an innovative technology to identify labile proteins, using libraries of proteins fused to green fluorescent protein (GFP) to monitor protein degradation. We will make GFP-cDNA expression libraries by fusing cDNA downstream from the C terminus of GFP. GFP can be detected in real time in...