Ridgeway Biosystems, Inc.

Cleveland, OH 44195

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $1.16MM
First Award Date 08/01/01
Most Recent Award Date 04/01/04

Key Personnel

Last Name Name Awards Contact
Leaman Douglas W Leaman 1
Xu Zan Xu 2
Cramer Hagen Cramer 4

7 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/04 - 10/31/04

DESCRIPTION (provided by applicant): Severe acute respiratory syndrome (SARS) is a newly recognized illness that has rapidly spread throughout Asia, North America and Europe. SARS has been found to be a highly infectious disease with high mortality, considerable occupational hazard, and no specific therapy. On July 5, the World Health Organizat...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/11/04 - 02/28/05

DESCRIPTION (provided by applicant): RNase L is a ubiquitous expressed latent ribonuclease, which is naturally activated by 2-5A (2',5' linked oligoadenylate). RNase L mediates antiviral and proapoptotic activities of interferon. Recently, it has also been mapped to a candidate gene for hereditary prostate cancer (HPC1). In this study, RNASEL mu...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 08/08/03 - 07/31/04

DESCRIPTION (provided by applicant): The ribonucleoprotein complex telomerase has been implicated in the establishment and progression of many different types of tumors. Telomerase activity is detected in roughly 80 percent of all tumor cell types, but is absent in most normal cells. Thus, the disruption of telomerase activity is a particularly ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/03 - 01/31/05
PI: Zan Xu

DESCRIPTION (provided by applicant): HCV is a significant human pathogen that has chronically infected 170 million people worldwide, including 4 million Americans. Clinical outcomes of HCV infections include cirrhosis and hepatocellular carcinoma. This year an estimated 10,000 individuals are expected to die from HCV infections in the U.S. and ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 04/30/04

DESCRIPTION (provided by applicant): The ribonucleoprotein complex telomerase has been implicated in the establishment and progression of many different types of tumors. Telomerase activity is detected in roughly 80% of all tumor cell types, but is absent in most normal cells. Thus, the disruption of telomerase activity is a particularly attrac...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/03 - 08/31/03
PI: Zan Xu

DESCRIPTION (provided by applicant): Inflammatory diseases represent increasing health care cost to American people. For many chronic inflammatory diseases (asthma, rheumatoid arthritis, bowel inflammatory diseases, etc.), there are no effective treatment. With the increase in the aging population of American society, this problem becomes aggr...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/01 - 07/31/04

DESCRIPTION (Adapted from Applicant's Abstract): Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in infants, young children and the elderly, particularly those that are institutionalized. It is the most common cause of viral bronchiolitis and pneumonia in children, and outbrea...