Mitosciences, Inc.

Eugene, OR 97403

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $1.58MM
First Award Date 06/07/04
Most Recent Award Date 05/15/10

Key Personnel

Last Name Name Awards Contact
Marusich Michael F Marusich 5

5 Awards Won

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-07-281
Budget: 05/15/10 - 04/30/11

DESCRIPTION (provided by applicant): Highly Active Anti-Retroviral Therapy (HAART) used to treat HIV/AIDS has serious side-effects, including metabolic complications from mitochondrial toxicities that can be life-threatening, and limit effectiveness and patient compliance. Adverse metabolic effects are now managed by adept clinicians who monito...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/07 - 02/29/08

DESCRIPTION (provided by applicant): Mitochondrial dysfunction underlies the pathology of many disorders, including inherited mitochondrial diseases, many degenerative diseases, and the adverse effects of certain therapeutic drugs. At present there are no reliable standardized methods for detection and analysis of these defects. Our goal is to m...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/06 - 02/28/07

DESCRIPTION (provided by applicant): Mitochondrial dysfunction underlies the pathology of many disorders, including inherited mitochondrial diseases, many degenerative diseases, and the adverse effects of certain therapeutic drugs. At present there are no reliable standardized methods for detection and analysis of these defects. Our goal is to m...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/15/05 - 05/31/06

DESCRIPTION (provided by applicant): HAART is an effective treatment for HIV infection but can cause serious metabolic complications including lacticacidemia, lipodystrophy, peripheral neuropathies, and cardiomyopathies. There is considerable evidence that the metabolic complications are the result of unintended mitochondrial toxicity of HAART. ...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/07/04 - 05/31/05

DESCRIPTION (provided by applicant): Mitochondria play a key role in cellular energy metabolism: they are the seat of oxidative phosphorylation (OXPHOS), which produces 98 percent of all the ATP utilized by mammalian cells. OXPHOS is catalyzed by 5 large, membrane-bound, protein complexes together made up of 90 polypeptides. Substrate entry into...