Chemdiv, Inc.

San Diego, CA 92121

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $1.05MM
First Award Date 05/01/04
Most Recent Award Date 08/01/07

Key Personnel

Last Name Name Awards Contact
Okun Ilya Okun 5

5 Awards Won

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-06-07
Budget: 08/01/07 - 01/31/09
PI: Ilya Okun

DESCRIPTION (provided by applicant): Development of drugs based on the MC2R antagonists will directly benefit children with CAH and Cushing's diseases, and will help us to understand MC2R's role in metabolic pathways. The long term goal of this project is to discover small molecule inhibitors of MC2 receptor and develop drug to treat several met...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-21
Budget: 05/01/07 - 04/30/08
PI: Ilya Okun

DESCRIPTION (provided by applicant): Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism required for the addition of CO2 to acetyl-CoA to make malonyl-CoA. In mammals, malonyl-CoA serves as a precursor for the synthesis of fatty acids but it also regulates fatty acid oxidation in mitochondria. There are two ACC isozymes in hum...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-06-07
Budget: 08/01/06 - 07/31/07
PI: Ilya Okun

DESCRIPTION (provided by applicant): Development of drugs based on the MC2R antagonists will directly benefit children with CAH and Cushing's diseases, and will help us to understand MC2R's role in metabolic pathways. The long term goal of this project is to discover small molecule inhibitors of MC2 receptor and develop drugs to treat several me...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/04 - 03/31/05
PI: Ilya Okun

DESCRIPTION (provided by applicant): The production of adrenal gland hormones, including cortisol and androgens, is regulated by pituitary ACTH (adrenocorticotropin hormone), which acts via the melanocortin-2 receptor (MC2R) to stimulate steroid production. The ability to antagonize ACTH action would greatly facilitate the care of several clinic...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/04 - 04/30/05
PI: Ilya Okun

DESCRIPTION (provided by applicant): The long-term objectives are to discover and develop new drugs for the treatment of obesity in humans. In Phase I, new drug lead candidates will be found by screening selected libraries drawn form Chemical Diversity Labs' collection of 550,000 publicly available chemical compounds. Screening candidates will b...