High Throughput Genomics, Inc.

Tucson, AZ 85706

SBIR Award Summary

Total Number of Awards 20
Total Value of Awards $6.34MM
First Award Date 03/01/00
Most Recent Award Date 06/01/14

Key Personnel

Last Name Name Awards Contact
Martel Ralph R. Martel 2
Seligmann Bruce E. Seligmann 15
Felder Stephen Felder 1
Thompson Debrah Michele Thompson 3

20 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 06/01/14 - 05/31/15

This Phase II proposal will complete the development of an innovative sequencing platform (NPSeq) based on feasibility demonstrated in Phase I. This platform uses a nuclease protection assay combined with universal PCR to produce targeted sequencing libraries. The lysis-only protocol means there is no need to extract RNA or DNA or to reverse tra...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 06/01/14 - 05/31/15

This Phase II proposal will complete the development of an innovative sequencing platform (NPSeq) based on feasibility demonstrated in Phase I. This platform uses a nuclease protection assay combined with universal PCR to produce targeted sequencing libraries. The lysis-only protocol means there is no need to extract RNA or DNA or to reverse tra...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-12-088
Budget: 09/01/13 - 05/31/14

This Phase II proposal will complete the development of an innovative sequencing platform (NPSeq) based on feasibility demonstrated in Phase I. This platform uses a nuclease protection assay combined with universal PCR to produce targeted sequencing libraries. The lysis-only protocol means there is no need to extract RNA or DNA or to reverse tra...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-050
Budget: 08/01/12 - 07/31/13

DESCRIPTION (provided by applicant): miRNA biomarkers related to Alzheimer's disease (AD) that may be useful as a diagnostic tool or in elucidating the mechanisms of disease and discovery of novel therapeutics will be identified using a novel whole transcriptome qBead" X-MAP-based assay (not yet launched commercially). Biomarkers will be identif...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-10-050
Budget: 08/15/11 - 07/31/12

DESCRIPTION (provided by applicant): miRNA biomarkers related to Alzheimer's disease (AD) that may be useful as a diagnostic tool or in elucidating the mechanisms of disease and discovery of novel therapeutics will be identified using a novel whole transcriptome qBead" X-MAP-based assay (not yet launched commercially). Biomarkers will be identif...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 07/01/11 - 12/30/12

DESCRIPTION (provided by applicant): Sequencing is very powerful for identifying differences in genomic DNA that may regulate cell function and diseases, pre-dispose persons to certain diseases, or warn of adverse drug metabolism. It provides a basis for identifying differences in gene expression, though such applications have been limited and a...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-115
Budget: 02/01/11 - 01/31/13

DESCRIPTION (provided by applicant): There is currently no good way to screen for early stages of head and neck cancers caused by high risk types of human papillomavirus. The objective of this proposal is to develop a screening assay for dental patients to detect HPV+ head and neck cancer ("HNC") pre-symptomatically, based on the use of viral an...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 08/13/10 - 06/30/11

DESCRIPTION (provided by applicant): Sequencing is very powerful for identifying differences in genomic DNA that may regulate cell function and diseases, pre-dispose persons to certain diseases, or warn of adverse drug metabolism. It provides a basis for identifying differences in gene expression, though such applications have been limited and a...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-135
Budget: 08/01/10 - 07/31/11

DESCRIPTION (provided by applicant): This application is a first resubmission of a Phase I application. An area of special interest to NIAID for SBIR/STTR applications is "Biomarkers of Host Immune Defense to Bioterrorism Pathogens". The use of microRNA's (miRNA) expressed in white blood cells as biomarkers to screen for infection is novel and p...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-397
Budget: 06/01/10 - 05/31/11

DESCRIPTION (provided by applicant): Phospholipidosis (PLDosis) or lipid metabolism disorders are a factor in many drug induced liver diseases. Drug induced, dose-dependent, alterations in the expression of sets of genes, whether direct cause or effect, can provide a molecular signature of the functional phenotypic effect(s) (e.g. adverse metabo...

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