Detroit R &D, Inc.

DETROIT, MI 48201

SBIR Award Summary

Total Number of Awards 14
Total Value of Awards $3.59MM
First Award Date 09/30/01
Most Recent Award Date 09/22/15

Key Personnel

Last Name Name Awards Contact
Kim Hyeong-Reh Choi Kim 2
Kim Hyesook Kim 12

14 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/22/15 - 06/21/16

Over 75% lung cancer patients are not diagnosed until at advanced or metastatic stage with <5% 5-year survival rate. A panel of microRNAs (miRNAs) in blood, urine and other body fluids were found to be lung cancer biomarkers. Thus, we propose to develop miRNA-based low-cost, untrasensitive (<1 ul serum needed) and fast responsive point-of-care...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/01/13 - 08/31/14

DESCRIPTION (provided by applicant): Structurally varied glycans displayed unexpectedly strong efects on inflammation and cancer progression. Glycan recognition by glycan-binding proteins is involved with physiological and disease-related cell adhesion or cell signaling. Tumor tissues secrete glycoproteins, which induce autoantibody production....

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-096
Budget: 09/01/12 - 08/31/13

DESCRIPTION (provided by applicant): Structurally varied glycans displayed unexpectedly strong efects on inflammation and cancer progression. Glycan recognition by glycan-binding proteins is involved with physiological and disease-related cell adhesion or cell signaling. Tumor tissues secrete glycoproteins, which induce autoantibody production....

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/06 - 08/31/08

DESCRIPTION (provided by applicant): Gene expression has been analyzed by throughput DMA microarrays which simultaneously monitor the expression of thousands of genes. However, mRNA expression of a gene may not correlate with protein expression because of the differences in rates of mRNA translation/degradation and post-translational modificatio...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/05 - 08/31/06

DESCRIPTION (provided by applicant): Gene expression has been analyzed by throughput DMA microarrays which simultaneously monitor the expression of thousands of genes. However, mRNA expression of a gene may not correlate with protein expression because of the differences in rates of mRNA translation/degradation and post-translational modificatio...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-03-13
Budget: 03/01/05 - 02/28/07

DESCRIPTION (provided by applicant): The long-term objective of this research project is to unveil the molecular signature of tumor cell invasion. Tumor invasion and metastasis are complex processes involving extracellular matrix (ECM) degrading proteinase activity and cell migration through the ECMs. Since mounting evidence suggests that ras e...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 08/31/06

DESCRIPTION (provided by applicant): Each year, approximately 120,000 babies are born in the US with a major birth defect and genetic and environmental factors play an important role. Embryonic differentiation pathways are highly conserved among vertebrates. The Xenopus laevis embryo is an established toxicology model with ease of chemical expos...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-AA-03-03
Budget: 09/01/04 - 08/31/06

DESCRIPTION (provided by applicant): Fetal Alcohol Syndrome (FAS) is defined as a pattern of growth retardation, characteristic facial anomalies and mental retardation in children born to alcoholic women. It is essential to begin remedial treatment of FAS children as early as possible. Therefore biomarkers linked to infants destined to develop...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-03-13
Budget: 03/01/04 - 02/28/05

DESCRIPTION (provided by applicant): The long-term objective of this research project is to unveil the molecular signature of tumor cell invasion. Tumor invasion and metastasis are complex processes involving extracellular matrix (ECM) degrading proteinase activity and cell migration through the ECMs. Since mounting evidence suggests that ras e...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/19/03 - 08/31/04

DESCRIPTION (provided by applicant): Each year, approximately 120,000 babies are born in the US with a major birth defect and genetic and environmental factors play an important role. Embryonic differentiation pathways are highly conserved among vertebrates. The Xenopus laevis embryo is an established toxicology model with ease of chemical expos...

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