Molecular Staging, Inc.

300 GEORGE STREET, 7TH FLOOR
New Haven, CT 06511

SBIR Award Summary

Total Number of Awards 7
Total Value of Awards $1.45MM
First Award Date 09/10/01
Most Recent Award Date 07/01/03

Key Personnel

Last Name Name Awards Contact
Kingsmore Stephen Francis Kingsmore 4 Message
Piccoli Steven P Piccoli 1
Lasken Roger Sender Lasken 5 Message

7 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/03 - 10/12/04

DESCRIPTION (provided by applicant): High throughput mRNA expression profiling studies are useful to evaluate changes in global gene expression under different physiological environments, e.g. diseased vs. normal tissue, drug-treated vs. untreated tissues, carcinogen/toxin-exposed vs. unexposed tissues. Often small quantity of total RNA samples,...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/03 - 09/30/04

DESCRIPTION (provided by applicant): The availability of large human genomic DNA sets of known ethnic origin remains a persistent problem for epidemiology and disease gene research. In this grant two valuable resources are combined to solve DNA availability problems. Molecular Staging Inc (MSI) has developed a technology, termed Multiple Displac...

Phase 2 SBIR

Agency: Department of Energy
Topic: 2003
Budget: 01/01/03 - 12/31/03

70555S02-II DNA sequencing is currently not possible when starting from single bacterial cells because of the limited amount of DNA present. Typical medical and biological samples contain a heterogeneous mixture of species; therefore, obtaining a sufficient amount of DNA requires a time-consuming and labor-intensive approach involving the i...

Phase 1 SBIR

Agency: Department of Energy
Topic: 2003
Budget: 01/01/03 - 12/31/03

70555S02-II DNA sequencing is currently not possible when starting from single bacterial cells because of the limited amount of DNA present. Typical medical and biological samples contain a heterogeneous mixture of species; therefore, obtaining a sufficient amount of DNA requires a time-consuming and labor-intensive approach involving the i...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/11/02 - 08/31/04

DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the most prevalent musculo-skeletal disease in the older adult population, characterized by chronic pain and life long disability. The current 'gold standard' for diagnosis of OA is radiology, but radiological changes occur relatively late in the disease after the bone tissue changes re...

Phase 1 SBIR

Agency: Department of Energy
Topic: 2002
Budget: 01/01/02 - 12/31/02

70555 Understanding the contributions of different bacterial strains or species in a complex bacterial community requires multiple experimental approaches to determine the biochemistry of each community member. One such approach involves the determinination of the complete DNA sequence of each prokaryote cell, a process that is difficult and ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-99-101
Budget: 09/10/01 - 08/31/02

A subset of human papillomavirus (HPV) types have been implicated in cervical cancer. The determination of the presence of the HPV types associated with cervical cancer may serve as adjunct to Pap smear screening of cervical samples. This analysis could reduce the incidence of invasive cervical cancer, while decreasing the human and economic cos...