Nuvogen Research, LLC

Tucson, AZ 85728

SBIR Award Summary

Total Number of Awards 16
Total Value of Awards $3.79MM
First Award Date 01/01/00
Most Recent Award Date 05/15/14

Key Personnel

Last Name Name Awards Contact
Felder Stephen Felder 6 Message
Kris Richard Martin Kris 11 Message
Montgomery Christopher Montgomery 2 Message

16 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 05/15/14 - 11/14/14

DESCRIPTION (provided by applicant): The long range goal of this project is to develop a high throughput method for companion diagnostics for cancer patients using next generation sequencing. It is a front end method compatible with all genome sequencing platforms, which preselects genes and labels samples in the first step to assure data integr...

Phase 2 SBIR

Agency: National Science Foundation
Topic: BC-2012
Budget: 01/01/12 - 12/31/12

This Small Business Innovation Research (SBIR) Phase II project is to address the high lethality of pancreatic cancer. Screening has begun with Phase IB funding, of natural products from the Sonoran Desert that have produced other promising drug candidates, testing effects on human pancreatic cancer cells. The objective of Phase II is to develop...

Phase 1 SBIR

Agency: National Science Foundation
Topic: BC-2010
Budget: 01/01/11 - 12/31/11

This Small Business Innovation Research (SBIR) Phase I project will help develop the first effective therapy for late stage hormone refractory Prostate Cancer (PCa). These late stage tumors rely on the Androgen Receptor (AR) pathway, but do not require androgen. Genetic changes allow tumors to use the pathway but escape the need for the hormone....

Phase 1 SBIR

Agency: National Science Foundation
Topic: BT9-2010
Budget: 01/01/10 - 12/31/10

This Small Business Innovation Research (SBIR) Phase I project is designed to discover compounds from a unique Natural Products Library that block the altered patterns of gene expression seen in pancreatic cancer. The extract and fraction library to be screened is from Dr. Gunatilaka at the University of Arizona and are derived from Sonoran dese...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 07/01/09 - 04/30/10

DESCRIPTION (provided by applicant): The overall objective of the work proposed in this grant is to find novel drugs that help to prevent metastasis. In Phase I, newly available natural product extracts will be tested to find compounds that specifically target genes that are critical for the Epithelial to Mesenchymal Transition (EMT) in several ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 03/15/08 - 02/28/09

DESCRIPTION (provided by applicant): In Phase I, newly available natural product extracts will be tested to find compounds that specifically target genes that are critical for the androgen receptor pathway of growth stimulation in recurrent prostate cancers. This is important because the androgen receptor pathway is deregulated and critical to r...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/05 - 08/31/06

DESCRIPTION (provided by applicant): This Phase II grant proposes to screen for 100,000 compounds that stimulate differentiation of adult human mesenchymal stem cells using a multiple mRNA assay, in 96-well plates. The assay quantifies induction of genes that signal differentiation to osteoblasts, chondrocytes, and other connective tissue types....

Phase 2 SBIR

Agency: National Science Foundation
Topic: 2005
Budget: 01/01/05 - 12/31/05

This Small Business Innovation Research (SBIR) Phase II project aims to develop a plate washer capable of washing very high-density plates, such as 1536 well plates, for ELISA and high-throughput screening assays. Currently, there are automated plate washers for 96 and 384 well plates, but there are none available for plates with ultra-...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/04 - 02/28/05

DESCRIPTION (provided by applicant): This Phase II grant proposes to screen for 100,000 compounds that stimulate differentiation of adult human mesenchymal stem cells using a multiple mRNA assay, in 96-well plates. The assay quantifies induction of genes that signal differentiation to osteoblasts, chondrocytes, and other connective tissue types....

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-00-126
Budget: 05/01/03 - 04/30/04

DESCRIPTION (provided by applicant): A quantitative high-throughput gene chip assay, ArrayPlateTM, based on nuclease protection has been developed for drug discovery. We will use this technology to develop two novel assays designed to screen for compounds that affect the expression of transcription factors and regulat...

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