Saneron Ccel Therapeutics, Inc.

Tampa, FL 33612

SBIR Award Summary

Total Number of Awards 15
Total Value of Awards $4.53MM
First Award Date 08/15/01
Most Recent Award Date 03/01/14

Key Personnel

Last Name Name Awards Contact
Willing Alison E Willing 1
Garbuzova-Davis Svitlana Nicolai Garbuzova-Davis 1
Saporta Samuel Saporta 1
Cameron Don F. Cameron 1
Sanberg Cyndy Davis Sanberg 1
Marshall William G Marshall 1
Low Walter C Low 1
Chen Jieli Chen 3
Tan Jun Tan 4
Nikolic William V. Nikolic 3
Kuzmin-Nichols Nicole A Kuzmin-Nichols 1

15 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-12-089
Budget: 03/01/14 - 02/28/15

DESCRIPTION (provided by applicant): Diabetes mellitus (DM) leads to a 3-4 fold higher risk of experiencing ischemic stroke. In addition, DM stroke patients are more prone to develop more and earlier white matter (WM) high-intensity lesions than non DM stroke patients. Treatment of stroke with tissue plasminogen activator (rtPA) at 2-3 hours aft...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-12-089
Budget: 03/01/13 - 02/28/14

DESCRIPTION (provided by applicant): Diabetes mellitus (DM) leads to a 3-4 fold higher risk of experiencing ischemic stroke. In addition, DM stroke patients are more prone to develop more and earlier white matter (WM) high-intensity lesions than non DM stroke patients. Treatment of stroke with tissue plasminogen activator (rtPA) at 2-3 hours aft...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-09-081
Budget: 03/01/12 - 02/28/13

DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL") provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further show...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-09-081
Budget: 03/01/11 - 02/29/12

DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL") provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further show...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-09-081
Budget: 09/15/10 - 02/28/11

DESCRIPTION (provided by applicant): In the past years, we have shown that human umbilical cord blood cells (HUCBC, U-CORD- CELL") provide cognitive recovery in animal models of neurodegenerative disease. Infusion of HUCBC resulted in reduced infarct volume as well as in rescue of behavioral benefits in an animal model of stroke. We further show...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-09-081
Budget: 02/01/10 - 01/31/12

DESCRIPTION (provided by applicant): There is a compelling need to develop therapeutic approaches specifically designed to reduce neurological deficits after stroke. Human umbilical cord blood cells (HUCBCs) treatment dose-dependently improves functional outcome after stroke. UCBCs are associated with a lower risk of graft-versus-host disease (G...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 09/30/08 - 08/31/10

DESCRIPTION (provided by applicant): Human umbilical cord blood is a rich source of hematopoietic stem cells that can be used to re-populate the blood and immune systems. In preliminary studies we have identified a novel population of non-hematopoietic cells that exhibit extensive self-renewal and markers characteristic of stem cells. We postula...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-07-81
Budget: 09/30/07 - 08/31/09
PI: Jun Tan

DESCRIPTION (provided by applicant): Modulation of the inflammatory cascade by several diverse strategies including A immunization, non-steroidal anti-inflammatory drug (NSAID) administration, and manipulation of microglial activation states have all been shown to reduce Alzheimer disease (AD)-like pathology, and cognitive deficits in AD transge...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/20/05 - 08/31/07

DESCRIPTION (provided by applicant): Human umbilical cord blood (hUCB) is a rich source of stem cells that exhibit multipotent properties. Previous studies have shown that hUCB cells can differentiate into neural cells under the appropriate environment conditions. SANERON CCEL, Inc. is focusing on the use of hUCB as a therapeutic approach for tr...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/05 - 04/30/07

DESCRIPTION (provided by applicant): Transplantation of human umbilical cord stem cells (hUCBC) has been shown to be effective in limiting infarct size and in the preservation of left ventricular function and anatomy in a rat model. These effects have been present in studies both utilizing and not utilizing immunosuppression. Whether immunosuppr...

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