Celsus Laboratories, Inc.

Cincinnati, OH 45241

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $438K
First Award Date 03/01/01
Most Recent Award Date 04/01/03

Key Personnel

Last Name Name Awards Contact
Cardin Alan D Cardin 3

3 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/03 - 09/30/04

DESCRIPTION (provided by applicant): The massive hypercoagulation response caused by the interaction of blood with the extracorporeal device during cardiopulmonary bypass (CPB) surgery requires high-dose unfractionated Heparin Sodium (UFH) to achieve circulation. Intimatan is in preclinical development as the preferred anticoagulant for cardiac ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/02 - 01/31/04

Restoration of blood flow to the ischemic coronary bed initiates the inflammatory process of reperfusion injury, progressive necrosis and apoptosis of myocytes, clinically known as myocardial infarction (MI). Although heparin has broad anti-inflammatory properties, its use as a cardioprotectant is limited by its potent anti-coagulant action. A s...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/01 - 08/31/02

DESCRIPTION: (Investigator's abstract) Thrombin bound to fibrin, the vessel wall and/or to extracorporeal surfaces is resistant to inhibition by heparin/antithrombin Ill (HAT). Intimatan, a dermatan disulfate semi-synthetically enriched in iduronic acid-N-acetyt-O-gafactosamine 4,6-O-d...